The superior vena cava (SVC) located in anterior mediastinum, Carries blood from the head, neck, upper extremities and upper chest. Rodeada by rigid structures and compress the upper originate vena cava syndrome (SVCS). The may be due to obstruction external compression (benign or malignant), Fibrosis or thrombosis. Venous hypertension produces head, neck and upper extremities azygos and deriving flow systems. Symptoms depend on the speed of obstruction and location is quick .If symptoms are intense. More often slow installation. Initial symptoms, Drowsiness, tinnitus, dizziness, cervical increased diameter. If Endures, cyanosis of the face, neck, upper limbs, altered state of consciousness. Examination: Plethora jugular, thoracic collateral circulation. The diagnosis clinical, in tele-ray, mediastinal masses, pleural effusion, lobar collapse, or cardiomegaly. The TAC defines the anatomy of mediastinal nodes and VCS, the site of obstruction and Provides guidance for needle biopsy, bronchoscopy or mediastinoscopy. Contrast venography, ultrasound and MRI are used to determine the site and nature of the obstruction. The treatment of malignant obstruction histological diagnosis by sputum requires cytology, biopsy or lymph. Treatment: General Measures and the underlying cause, if chemotherapy or radiotherapy neoplastic in thrombosis, thrombectomy plasminogen activator (TPA), streptokinase or urokinase. Aangioplastia intraluminal stent, bypass in malignant etiology no chemotherapy and radiotherapy with improvement. Driving urgent: Patients with cerebral edema, airway obstruction due to compression of the trachea, for airway edema, or cardiac output decreased in venous return. Mortality depends on the underlying cause.