Introduction: Toxoplasmosis is a disease caused by an obligate intracellular coccidia Toxoplasma gondii, which is transmitted by cats. In pregnant women, it is a concern because of the severe complications to the foetus. The objective of this study is to determine the toxoplasma serologic profile in pregnant women at the Brazzaville University Centre Hospital (CHUB). Materials and Methods: This is a cross-sectional study from September 2015 to March 2016 (6 months) which includes sera from pregnant women received at the Parasitology Mycology laboratory of the CHUB for Toxoplasma serology. Immunoglobulins G and M searches were done by immuno-analysis (Biomerieux, Mini-Vidas technology). The data was analysed by the IBM SPSS version 20 software. The comparisons of proportion is done by the khi 2 test. The level of significance of statistical data were fixed at 5%. Results: The mean age of pregnant women included in our study was 27, 8+/- 6,84 with the extremes ages of 15 and 44 years. Toxoplasma seroprevalence in this study is 47,2% (68/144). The types of immunoglobulins (Ig) retrieved were IgG alone in 45,1% of cases (65/144), IgG associated to IgM in 2,8% of cases (4/144). Serological profiles were: no immunity (52,1%) immunised (41%), recent infection (1,4%) active infection (2,8%) equivocal result (2,8%). Conclusion: Toxoplasmosis is a zoonosis which represents a real public health issue in our environment, even when the level of immunised pregnant women seems high.

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Human African trypanosomiasis is a neglected tropical disease about to be eliminated as a public health problem. It afflicts rural populations, particularly adults engaged in hunting and fishing activities in endemic homes. Left untreated, the disease is 100% fatal in an array of dormant cachexia. Vertical transmission from mother to child is rare but proven. We report a case of Human African Trypanosomiasis in an 11-year-old girl who has never been to an endemic area and who has no other risk exposure factor apart from the fact she was born from mother who was affected by the disease and treated for 10 years during pregnancy. The diagnosis was made after the analysis of the LCS notifying 144 elements with the presence of numerous trypanosomes. The patient was classified into the second period and treated with NECT for 10 days.