Calcitonin has been helpful in the treatment of osteogenesis imperfecta tarda inhibiting bone mineral resorption. The experience with salmon calcitonin in the early treatment of osteogenesis imperfecta congenita is very limited. Here we report an infant with this disorder treated with calcitonin from 3 to 15 months of age with clinical and radiographic improvement.

A case is reported of a 4-year-old female with an adrenal cortical carcinoma that developed at the site of a previously removed adrenal gland. Initially, the tumor was only virilizing, but with time, it also became the source of a large secretion of glucocorticoids and, to a lesser degree, mineralocorticoids. It is one of the largest and most functional tumors described in a child.

determined by colorimetric method. enzymatic, as well as the concentration of 4-hydroxynonenal was determined as a marker of oxidative stress. Results: e values of 4-hydroxynonenal in the control population ranged between 2.61 and 6.83 µmol/L and in diabetics 28.99 and 73.74 µmol/L., finding statistically significant differences between both populations, as well as in the lipid profile and glycemia between both groups. Conclusion: e results show an elevation of lipid peroxidation in diabetic patients, which is indicative of oxidative stress and additional risk in these patients that could lead to chronic complications of type 2 diabetes.

No abstract

No abstract