Introduction: photobiomodulation was showed positive effects on bone healing, however, several studies search safe protocols and dosimetry, beyond good experimental models. Thus, the present study aimed to conduct a systematic review of photobiomodulation (PBM) effects on bone healing increase, focusing on animal experimental models. Revision: the studies search on the PBM use in bone repair was carried out in the PubMed / MEDLINE and Lilacs databases, excluding studies that included systemic conditions and biomaterials or medications use. Sixteen studies were selected, within the inclusion and exclusion criteria stipulated. Animal models included rats (n = 14) and rabbits (n = 2). The laser parameters applied ranging between 650 nm and 830 nm and the power density ranging from 0.03 W to 6 W. Animal models were mainly concentrated in rodents, and the most utilized defect type was the tibial bone defect with 2.5 mm of diameter. Conclusion: through this review we concluded that the location and size of the defects, as well as the laser irradiation parameters are diverse and have shown the lack of consensus on the topic, however the results for using PBM therapy are encouraging.