Sarcoidosis is a chronic multisystem granulomatous inflammatory disorder. It can present acutely which is known as Löfgren's syndrome. The diagnosis may be missed if clinicians are not aware of its classic presenting features and the appropriate diagnostic investigations.
A case of aortitis in a patient undergoing adjuvant cisplatin and topotecan
chemotherapy for cervical cancer following presentation with pyrexia of unknown
origin and raised inflammatory markers is presented. Although many chemotherapy
agents are known to cause small vessel vasculitis and there are several reported
cases of large vessel vasculitis following gemcitabine chemotherapy, there is
only one previously described case of aortitis following cisplatin
administration. This case is presented with corresponding CT and
18
F-FDG PET-CT imaging with discussion of the literature regarding
vasculitis and chemotherapy.
SUMMARYHypoglycaemic haemiparesis (HH) is an uncommon but important presentation to the emergency department, and it often mimics stroke and is therefore frequently misdiagnosed by clinicians. The mechanism of haemiparesis is not fully understood. This case outlines a diabetic elderly woman, who had been having frequent hypoglycaemic episodes and presented to paramedics with hypoglycaemia associated with a right-sided haemiparesis. She was immediately transferred to the local stroke centre after presenting to the emergency department. CT and MRI did not fit in with her presenting neurology. Her weakness resolved, after normoglycaemia was achieved with dextrose infusion; however, she was reported to be more sleepy and drowsy than usual. After extensive and costly investigations during her prolonged inpatient stay, her unifying diagnosis was an HH which triggered of a hypoactive delirium.
BACKGROUND
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