Introduction. Liquorrhea is a leakage of cerebrospinal fluid (CSF) into an air cavity of the skull base through an osteomeningeal breach which can exit through nos and / or ear. Highlighting the breach and closing it is sometimes very difficult. The aim of this work was to study cerebrospinal fluid liquorrhea management in our work environment. Method. This was a retrospective study over 05 years (2010)(2011)(2012)(2013)(2014). We included any cases of liquorrhea managed in the neurosurgery department of Yalgado Ouédraaogo teacching hospital in Ouagadougou. Results. Thirty-five cases were included, they were 34 male and 1 female. The average age was 31.6 years. Liquorrhea was the reason for admission in 11 cases. Physical examination found rhinorrhea in 24 cases, otorrhea in 9 cases and oto-rhinorrhea in 2 cases. A fracture line was objectified one CT scan in all patients. This fracture line could explain the liquorrhea in 24 cases. Conservative treatment was performed in 33 cases. Two patients were opered. Outcome was favorable in 33 patients. One patient died of meningitis. Conclusion. Highlighting of the breach was difficult in our work context where CT-scan can provide good orientations. Treatment was essentially conservative; prognosis very often favorable except in the event of a complication such as meningitis.

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