Background: The burden of tuberculosis is high in Nigeria as in other developing countries. The administration of BCG vaccine to neonates is essential in the control of tuberculosis. A scar usually develops 6-8 weeks later at the site of vaccination, which can be used clinically as a proof of vaccination. Not all vaccinated infants however, develop a BCG scar. Objectives: To determine the prevalence of scar formation postvaccination and to unravel, if present, any factors responsible for scar failure. Methods: Two hundred and fourteen children were consecutively recruited from those who presented for immunization in the

Although the calibre of the airway is kept patent by multifactorial control system, there is evidence that the calibre of the bronchi varies with time of the day in normal subjects. Asthma is now known to be a chronic inflammatory disease and this chronic inflammation causes hyperreactivity and lability in the airway. Therefore, asthma is characterised as a disease where respiratory symptoms are based on large variation in airway calibre leading to variations in resistance to airflow over a short period of time. Method: Normal non-asthmatic children leaving within 10km of University of Benin Teaching Hospital (UBTH) and whose parents work at UBTH were recruited. These subjects aged 5-15 years were initially matched with an index asthmatic case both for sex and age (within six months range). Using a questionnaire the control were screened to exclude any case with history of respiratory, cardiac or any form of active disease or chest deformity or family history of asthma. This was followed by weight and height determination. Both the subject and control were then instructed on the correct use of the mini Wright Peak Flow meter and how to record it in the diary provided. After five days of measurement, the diaries were collected and the PEFR were analysed. Results: Two hundred and ten (210) asthmatics and one hundred and eighty healthy children completed the study. The two groups were