Background/AimUrinary sucrose and fructose may serve as biomarkers of sugars intake, the latter which are thought to be underreported in dietary assessment. We examined associations of urinary sugars with reported sugars intake in adults recruited for a study on diet and chronic disease risk.MethodsHealthy, non‐smoking, weight‐stable adults (n=76) performed 3×24h urine collections (UC) and completed 3 multiple pass 24h dietary recalls over 10d. Results are shown for those (n=67; aged 18–58y, BMI 19–36kg/m2) who had ≥1 complete UC (urinary PABA recovery ≥85%). Urinary sugars were measured by an enzymatic kit (Roche) and mean daily amounts calculated. 3d mean intakes of sucrose, fructose and added sugars were computed with Nutrition Data System for Research (v.10/11). Plausible (n=52) and implausible EI reporters (n=15) were determined (Huang et al, 2005).ResultsMean(±SEM) urinary sucrose and fructose were 28±2 and 38±4 mg/d, respectively. Reported intakes were 56±5 (sucrose), 25±2 (fructose), and 84±7 (added) g/d. Urinary sucrose was significantly associated with dietary sucrose in the plausible sample (r=0.36; p=0.008) and non‐significantly in the total sample (r=0.19; p=0.12). A similar pattern was seen for urinary sucrose and added sugars intake. Urinary fructose and sugars intake were not significantly associated.ConclusionThese data provide strong evidence that foods containing sucrose and added sugars are underreported.Grant Funding Source: R01DK075862 and Purdue University

BACKGROUNDIndividuals with insulin resistance (IR) have been suggested to have more food cravings than those without IR, particularly sweet cravings. However, little research has been done in this area. We tested the hypothesis that individuals with IR would have more frequent and stronger cravings, perceive themselves as less able to ignore cravings, and ‘give in’ to cravings more often than those without IR.METHODSWe analyzed data from healthy, non‐smoking, weight stable adults (aged 18–58 y; BMI 19–35 kg/m2) who had participated in recent studies in our lab and reported energy intakes (EI) plausibly (within ±25% of energy requirement (Huang et al 2005)). Cravings were assessed by questionnaire (Hill et al 1991). IR was defined as homeostasis model assessment (HOMA) >1.775 (Esteghamati et al 2010).RESULTSIndividuals with IR (n=28) had higher BMI (p=0.014) and were slightly more active (p=0.08) and younger (p=0.11) than those without IR (n=34). After controlling for confounders, those with IR had 45% less frequent cravings than those without IR (p=0.04), but no other craving variables differed significantly by IR status.CONCLUSIONSOn average, cravings were not experienced differently in those with IR versus without IR. Nevertheless, perceived cravings may be important if they trigger intake of foods that may exacerbate IR. [Funding: DK075862]