IntroductionPostoperative blood loss after prostate surgery is thought to be associated with an increase in urinary fibrinolytic activity. Tranexamic acid (TXA) is both a potent inhibitor of plasminogen and urokinase activators and a low molecular weight substance that is excreted unchanged in the urinary tract and can be administered both orally and intravenously. We investigated the effect of TXA on the amount of blood loss during transurethral resection of the prostate (TURP).Materials and methodsForty patients with registry numbers ending in even numbers were allocated to the treatment group; those ending in odd numbers were used as controls and received no treatment. The treatment group received 10 mg/kg TXA by intravenous infusion during the first half hour of the operation, while the control group of patients received no medication. Serum hemoglobin was measured before and after surgery. The volume and hemoglobin concentration of the irrigation fluid, resected prostate weight, and duration of resection were recorded.ResultsThe mean loss of hemoglobin per gram of resected prostate tissue was 1.25 g in the TXA group and 2.84 g in the control group. Total hemoglobin loss in the irrigating fluid and hemoglobin loss per 1 gram of prostate tissue was lower in the group of patients given TXA than in the control group (p = 0.018 and p <0.001).ConclusionReduced bleeding during TURP as a result of TXA treatment may lead to better surgical conditions and, as a consequence, shorter operative times and lower irrigating fluid volumes.

IntroductionGuy's Stone Score and S.T.O.N.E. Nephrolithometry nomograms have been introduced for systematic and quantitative assessment of kidney stones.The aim of this study was to reveal the value of two scorings systems, Guy and S.T.O.N.E, most frequently used for predicting postoperative stone-free status prior to Percutaneous Nephrolithotomy (PCNL), in the prediction of postoperative results of PCNL.Material and methodsWe retrospectively examined patients who underwent PCNL. Preoperative abdominopelvic computerized tomography images of these patients were reviewed and scored according to the Guy and S.T.O.N.E. systems.The relationship between the Guy and S.T.O.N.E. scores, and their postoperative stone-free status, complications based on Clavien system, operation time, fluoroscopy time and period of hospitalization was compared.ResultsWe identified a total of 102 patients who underwent PCNL between 2010 and 2014, having met the inclusion criteria.The relationships between the total S.T.O.N.E score and Clavien score (p <0.001); time of operation (p = 0.012) and stone-free status (p <0.001); Guy stone score and Clavien score (p <0.001); and period of hospitalization (p <0.001) and time of operation (p <0.001) were found to be statistically significant. There was no statistically significant relationship between Guy score and stone-free status and no statistically significant relationship was found between fluoroscopy time and both stone scoring systems.ConclusionsGuy and S.T.O.N.E. scoring systems may be used as effective instruments particularly for predicting postoperative complications.

Background : In the present study, we assessed the efficacy and morbidity of periprostatic local anesthesia before transrectal ultrasound (TRUS)-guided biopsy of the prostate.

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Objective To compare the results of conventional trans-remeasured and the values compared with those before treatment and between the groups. urethral electroresection of the prostate (TURP) and transurethral electrovaporization (TUEP) in patientsResults The improvements in symptom score, maximum flow rate and residual urine were slightly better after with symptomatic benign prostatic hyperplasia.Patients and methods The study comprised 46 patients TURP than after TUEP but the differences between treatments were not statistically significantly different. with moderate or severe symptoms of prostatism and a maximal flow rate of <15 mL/s. Pre-operatively, all However, TUEP used slightly less irrigant solution, allowed earlier removal of the urethral catheter, patients underwent a digital rectal examination and the determination of prostatic volume by ultrasonogra-required no blood transfusions and was easier to perform. phy, and a symptom score, the maximal flow rate, post-void residual urine, routine biochemical variables Conclusion Although the improvements in the objective variables 3 months after TUEP were almost the same and serum prostate specific antigen were measured. The haematocrit and blood Na+ levels were also as after TURP, there were advantages in using less resources; further studies with more patients and a determined pre-operatively and again 24 h after the operation. Patients were divided randomly into two longer follow-up are required to determine the efficacy and safety of this procedure. groups; the first underwent a conventional TURP and the second TUEP using 240-300 W of cutting current.