Introduction:Dermatoglyphics is the scientific study of ridges present on fingers, palms and soles. Female reproductive cancers shorten lifespan in women because of high mortality and morbidity. Detection at preinvasive and micro-invasive stages makes near 100% survival of cancer patients. Genes that take part in the development of finger and palmar dermatoglyphics distinguish cancer patients from general population. It is possible that these genes also predispose to the development of malignancy. Materials and Methods:Materials for the study consists of finger prints of outpatients and inpatients of the Department of OBG, Tirupati and Cancer Hospitals in and around Tirupati, Nellore and Kadapa. The ink prints of each finger were collected from 76 female patients who were diagnosed of having reproductive system cancer by histopathology report. 76 normal females of 30 -60 years of age who are apparently normal are chosen randomly as control group.Results: Present study on different female reproductive cancers, 76 normal and 76 female reproductive cancer cases were studied. Among the 76 cancer cases 49 are of cancer cervix and other 27 cancer cases are from other types of female reproductive system cancers that include endometrial, ovarian, vulval, vaginal, tubal and a combination of cervix and vagina. For statistical analysis, the total cases were categorized into control, cancer cervix and female reproductive cancers other than cancer cervix. Conclusion:Since many investigations are needed to confirm the diagnosis of cancers, dermatoglyphics can be used as a screening procedure to define indications for laboratory procedures.
Background: The present study was conducted to assess knowledge, attitude, the practice of family planning and to study the determinants of fertility in different socio religious population in Tirupati, Andhra Pradesh, India.Methods: The present cross-sectional study was carried out among 150 study subjects using a self-administered questionnaire. The data was collected and analyzed with Epi info version 7.Results: Only 144 participants actively participated and given their consent. Majority of them have knowledge about any one method of contraception. An average of both Muslim and Hindu religion have known about the natural contraceptive methods, oral contraceptive pills and IUCD was equal and an average of 11-12% of the participant were aware about side effects of oral contraceptive pills. The objections to contraceptive preventing women from using contraceptives coming from husbands and mother-in-law were strongly agreed/agreed in Hindu and Muslim population almost similar. The religious believes were strongly agreed/agreed in Muslim women than Hindu. Even though most of the participants visited or consulted with health care professionals in health center for family planning and 3/4th of them were using contraception. While comparing the four proximate determinants of fertility, index of contraception had greater impact on fertility than others.Conclusions: The present study highlighted that most of the women have not practised and have less knowledge about modern contraceptive methods. Innovative approaches have to be planned, tested and implemented to ensure their access to information, contraceptive methods and family planning services.
A number of classification techniques are prevailing in literature. Of them, one of the most important techniques is the Receiver Operating Characteristic (ROC) curve. A multivariate extension of this technique is proposed in the recent years. This technique helps in classifying the objects/individuals into one of the two classes by considering two or more markers. The most important measure of an ROC curve is the Area Under the Curve (AUC) and it explains the accuracy and discriminating ability of the test under study. There are two intrinsic measures of ROC namely sensitivity (Sn) and specificity (Sp). Further, two ROC curves can be compared by comparing their measures. The practical application of the proposed inferential procedures is explained with the help of two real datasets namely, Indian Liver Patient (ILP) Dataset and Intra Uterine Growth Restricted Fetal Doppler Study (IUGRFDS) dataset. These inferential procedures are developed based on the measures of multivariate ROC (MROC) curve proposed by Sameera G, R Vishnu Vardhan and KVS Sarma [1].
Introduction: Female reproductive system cancers shorten lifespan in women because of high mortality and morbidity. The detection of pre-invasive and micro-invasive stages makes near 100% survival of cancer patients. Dermatoglyphics is the scientific study of fingerprints. Many genes which take part in the control of finger and palm dermatoglyphic development distinguished cancer patients from the general population. It is possible that these genes also predispose to the development of malignancy. Since many investigations are needed to confirm the diagnosis of cancers, dermatoglyphics can be used as a screening procedure for planning preventive care if a specific pattern is known for a cancer. Aims and Objectives: To analyze the prints of different cancers, to analyze the results, compare with controls and observe the differences in main parameters of dermatoglyphic patterns and to determine a specific pattern for specific cancers. Subjects and Methods: This is a prospective, observational and an analytical study started after the approval by Institutional Ethical Committee of S.V. Medical College, Tirupati. The material for the study consisted of finger and palm prints of outpatients and inpatients of the Department of OBG, Tirupati, Cancer Hospital in and around Tirupati, Nellore and Kadapa. The ink prints of each finger and palm were collected and analyzed. Results: Ridge counts, digital patterns and main line formulae observed in different cancers in the present study were analyzed and presented. Mean TFRC was higher in normal group. Greater AFRC was observed in cancer cervix patients when compared to controls. In the present study, there is no difference (p> 0.05) in a-b ridge count among carcinoma of cervix and control group in both hands. Differences of mean atd, tad and tda angles among the groups are not statistically significant (P>0.05).The most common Cmain line termination pattern of cancers are U followed by R and then Ab. IV interdigital area of both hands presented less incidence of loop pattern in cancer cases when compared to normal group. Special findings in respective cancers are discussed separately and they are not found in any other literature. Conclusion: There are very limited studies in literature on dermatoglyphic pattern in female reproductive cancers. Though the cost of prints is less, more time and skilled human resources are required for their analysis. Study sample size of controls and cases to be increased. Public should be enlightened about dermatoglyphics. If large number of studies are done and a specific pattern is established for specific cancers, then it becomes cost-effective to people so that a risk is predicted beforehand in any disease and preventive methods can be employed at an early age as the dermatoglyphic patterns do not change in a life time.
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