Cancer is one of the leading causes of death in the world. American Cancer Society reported 12 million new cases of malignancy diagnosed worldwide in 2007, with 7.6 million people dying from the disease. Plant-derived molecules have played an important role in cancer chemotherapy. Many cytotoxic plant-derived molecules such as vinblastine, vincristine, navelbine, etoposide, teniposide, taxol, taxotere, topotecan and irinotecan have been approved as anticancer drugs. Flavonoids, a plant-derived molecule has shown to regulate proliferation and cell death pathways leading to cancer. Some Flavonoids have already entered in clinical trials, among them Quercetin is emerging as prospective anticancer drug candidates and its prodrug QC12 has entered in phase-I clinical studies. In this review authors have tried to cover in brief but comprehensive way, the chemistry related to synthesis and uses of "Quercetin & its derivatives" with special emphasis on the anticancer properties.

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Objective: To find out the effect of Pilates on Pain and core muscle endurance in females with chronic low back pain. Materials and Methods:A sample of 20 females with chronic non specific low back pain with age group of 25 -40 years participated in the study. Each subject were given10 minutes of walk before 40 minutes of Pilates for 5 days a week ,5-6 repetition of each exercise for 4 weeks, exercises incorporated were pelvic tilts, supine leg circles, side lying circles, side lying clamps, prone lying cobra stretch, prone lying leg raise, quadruped superman and seated spine twist. Basic commands regarding the positioning, activation and engagement of core along with breathing control were given to the subjects. Pre and post reading of pain using VAS and core muscle endurance using Plank endurance test was taken. The effect of Pilates was then analyzed. Result and Conclusion:There was significant improvement in pain and core muscle endurance after 4weeks of Pilates in females with non specific chronic low back pain.

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