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SynopsisA commercial sample of poly (dA-dT), a copolymer of 'L'-deoxyri~)osyladeiiositie (dA) and 2'-deoxyribosylthymiditie (dT) of perfectly altertiat itig sequence, was fractionated by chromatography on Agarose gel. Paucidisperse fractions of different molecular size were obtained. The plot of log s "~~, ,~ values shows a linear dependence on Ve. The biioyatit densities of individual fractions do riot, differ over the moleciilar size ratige st,udied. 0 1 1 the other hand, the heat-itidiiced hyperchromic eft'ect was fortiid to depend oii molecbiilar size below a certain limit, SO^^,,^ = 4.12 S.

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