A male infant was found to have bilateral exudative retinopathy at 6 months of age. A month later severe aplastic anaemia was diagnosed, eventually leading to the infant's death. Additional features of this seemingly new syndrome were intrauterine growth retardation, fine sparse hair, fine reticulate skin pigmentation, ataxia because of cerebellar hypoplasia, cerebral calcifications, extensor hypertonia, and progressive psychomotor retardation.

A survey was conducted on children attending 30 primary schools (15 each for boys ad girls) in Al-Ain City of United Arab Emirates (UAE) to assess the impact of asthma on school absenteeism. There are 28,447 primary school children (50% boys and 50% girls) aged 6-14 years in the Al-Ain Educational District, all of whose school health records were investigated with respect to school absence caused by asthma during the academic year 1991-1992. Results showed that overall 1910 (6.7%) pupils were diagnosed as having asthma and wheezing during the preceding year by school doctors and nurses. Out of 14,217 boys, 1146 (8.1%) had asthma and wheezing, and 764 of 14,230 girls (5.4%) had the same condition. Overall 1,255 (4.9%) pupils were absent from school for at least 1 day during the year. Of 1146 boys with wheezing or asthma, 707 (62%) missed at least 1 day of school due to asthma, and of 764 girls who were asthmatic or wheezing, 548 (72%) missed school for at least 1 day in the year. There was a very highly statistically significant difference between sexes of children who were asthmatic or wheezing and missed school at least 1 day (p < 0.0001). Absenteeism most commonly occurred during spring for both boys (42%) and girls (45%). Absence from school due to asthma occurred least during autumn for both boys (26%) and girls (22%). This study confirms that asthma is a common chronic disease among primary school children in Al-Ain, UAE, and is a common cause of absenteeism from school.

The aim of this study was to determine the prevalence of asthma among United Arab Emirates school children aged 6-14 years. A cross-sectional study of 850 school children living in both urban and rural areas (average age 9.36 +/- 2.11 years, 46.8% boys and 53.2% girls) was conducted using self-administered questionnaires between October 1992 and May 1993. The population sample had a high prevalence rate of diagnosed asthma (13.6%), breathlessness or tightness in chest (9.7%), allergic rhinitis (22.9%), and nocturnal cough (8.9%). Allergic rhinitis was the most frequently seen respiratory illness when compared to other respiratory symptoms. The frequency of asthma, allergic rhinitis and eczema among parents reflected the same pattern as that seen in the children. Prevalence rate of asthma was not significantly higher in fathers (5.9%) than in mothers (5.3%). The differences between the sexes were not significant in any of the age group studied for any of the allergic conditions, except for diagnosed asthma in which the prevalence rate in males was significantly higher than that in females. On the whole, the prevalence rate of all the conditions increased with age. But the frequency of allergic rhinitis symptoms was significantly higher in mothers (16%) than in fathers (10.8%). These results are consistent with those obtained in neighbouring gulf countries and are higher than those of some developed countries, but the differences are not statistically significant.

This study investigated the association of asthma, allergic rhinitis, and eczema in United Arab Emirates (UAE) schoolchildren with allergic conditions in their parents. A cross-sectional, population-based study among schoolchildren aged 6-14 years was conducted in Al-Ain City, UAE. The field survey was conducted from October 1992 to May 1993. A questionnaire was distributed to 850 UAE government school students from representative, randomly selected schools with a majority of UAE nationals. The student and both or either of the parents were present during the interview. A detailed clinical history of asthma and wheezing in the target children and a history of asthma and allergic rhinitis in their parents and siblings were obtained. It was found that 13.1% of asthmatic children had mothers with asthma (relative risk (RR) = 2.67; 95% confidence intervals (CI) = 1.65-4.35), and 15.2% had fathers who were asthmatic (RR = 2.85; 95% CI = 1.81-4.49). This contrasted with 4.4% of nonasthmatic children who had fathers with asthma, and 4.1% who had mothers with asthma. A similar pattern was seen with symptoms of allergic rhinitis when it was found that 34.3% of children who had asthma had mothers with allergic rhinitis (RR: 2.74; 95% CI: 1.90-3.94). The corresponding figure for fathers was 12.7% (RR: 0.92; 95% CI: 0.5-1.7). The frequency of either parent of the asthmatic children having allergic rhinitis was 28.6%; for both parents, it was 14.5%. It was also found that asthmatic children had 12.5% of their fathers, 32.8% of their mothers, 26.4% of either of their parents, and 33.3% of both their parents suffering from allergic rhinitis.(ABSTRACT TRUNCATED AT 250 WORDS)

The aim of this paper was to study the effect of pets and other domestic animals on bronchial asthma among United Arab Emirates (UAE) schoolchildren aged 6-14 years. A cross-sectional study of 850 schoolchildren living in both urban and rural areas (average age 9.36 +/- 2.11 years, 46.8% boys and 53.2% girls) was conducted using self-administered questionnaires between October 1992 and May 1993. Prevalence rate for asthma, rhinitis, wheeze, cough, and eczema in children from families with and without animals were investigated. A total of 40.7% of families studied were found to keep animals in their homes. Children from families with animals were found to have a significantly higher prevalence rate of respiratory symptoms than those without. The prevalence rate for asthma in children with animals was found to be twice that of children without (RR: 2.03; 95% CI: 1.40-2.95). The risk of having chronic cough (RR: 1.93; 95% CI: 1.21-3.10), breathlessness/chest tightness (RR: 2.53; 95% CI: 1.59-4.02), chronic wheeze (RR: 2.10; 95% CI: 1.20-3.67), allergic rhinitis (RR: 1.53; 95% CI: 1.17-2.00) was significantly higher in children with animals than in children without. Similarly, the risk of having eczema (RR: 2.55; 95%, CI: 1.74-3.75) was significantly higher among children with animals than among those without. Overall, there was a highly statistically significant difference in the prevalence of asthma, wheeze, nocturnal cough, eczema, and rhinitis between children in families with animals and those without (p < 0.0001).(ABSTRACT TRUNCATED AT 250 WORDS)