Twenty-three male Black African and 23 male Caucasian subjects, ascertained as sedentary, participated in this study designed to determine whether there were differences in skeletal muscle histochemical and biochemical characteristics between racial groups. Muscle fiber type proportions (I, IIa, and IIb), fiber areas and activities of several enzyme markers of different energy metabolic pathways were determined from a biopsy of the vastus lateralis. Results indicated that Caucasians had a higher percent type I (8%, P less than 0.01) and a lower percent type IIa (6.7%, P less than 0.05) fiber proportions than Africans. No significant differences were observed between the two racial groups in the type IIb fiber proportion or in the three fiber type areas. Enzymes catalyzing reactions in phosphagenic [creatine kinase (CK)] and glycolytic [hexokinase (HK), phosphofructokinase (PFK), and lactate dehydrogenase (LDH)] metabolic pathways had significantly higher activities (about 30-40%) in the Black African group than in the Caucasian group (P less than 0.01). No significant difference was noted in the activities of oxidative enzymes [malate dehydrogenase (MDH), oxoglutarate dehydrogenase (OGDH), and 3-hydroxyacyl-CoA dehydrogenase (HADH)]. Consequently, the PFK/OGDH ratio was significantly elevated in Africans (P less than 0.05). The racial differences observed between Africans and Caucasians in fiber type proportion and enzyme activities of the phosphagenic and glycolytic metabolic pathways may well result from inherited variation. These data suggest that sedentary male Black individuals are, in terms of skeletal muscle characteristics, well endowed for sport events of short duration.
Objective: To investigate use and awareness of lawful and unlawful substances by amateur footballers in Yaounde, Cameroon. Methods: A total of 1116 amateur footballers (1037 male and 79 female) out of 1500 contacted participated in this study. They were divided into three groups: elite players (n = 314); local players (n = 723); female players (n = 79). They answered a questionnaire of 30 items grouped under six main topics: identification of players; use of lawful substances subject to certain restrictions on the International Olympic Committee (IOC) list; use of IOC banned substances; doping behaviour; awareness of doping; food supplements. The results of the questionnaire were scrutinised using Microstat software, and the level of significance was p<0.05. Results: (a) Use by our footballers of a banned substance (cocaine) and substances subject to certain restrictions (alcoholic drinks, methylated spirits, and banga (marijuana)). (b) Doping behaviour: use by our footballers of substances with similar effects to some IOC banned substances but not listed as such: tobacco, liboga, wie-wie (narcotic), bilibili (locally made alcohol drink). (c) A large intake of vitamin C (food supplements) in all three groups. In contrast, the footballers' knowledge of doping was vague. Conclusion: Preventive actions and an epidemiological study of doping among footballers are urgently required.
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