The presence of even mild diabetic complications has a significant impact on patients' quality of life. Early diagnosis and treatment is essential to help prevent deterioration of HRQOL in these patients.
Type II (non-insulin-dependent) diabetes mellitus is a common chronic illness with a prevalence as high as 8 % in many countries [1]. In Europe approximately 27 million people suffer from diabetes, 80±90 % of whom have Type II diabetes [2]. Due to increased life expectancy, increased frequency of diagnosis and lifestyle changes, the prevalence of this disease in Europe is expected to increase by 50 % over the next 15 years. Approximately 50 % of people with Type II diabetes are thought to be undiagnosed [3] because its onset is gradual and could precede diagnosis by up to 7 years [4].Diabetes imposes a substantial burden on both individuals [5] and health-care budgets. In the UK, annual diabetes costs were estimated at £ 547 million in 1995, with 64 % of these costs resulting from hospital in-patient care [6]. This large hospital care burden is a result of the treatment of retinal, renal, neuropath-
The Framingham risk equations can be unreliable when applied to the diabetic population, tending to underestimate an individual's probability of progressing to CHD; the equations perform marginally better in women than in men. The use of imputed mean HDL-cholesterol values improved the reliability of the estimates of risk.
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