No abstract

Mining gene expression data is growing rapidly to predict gene expression patterns and assist clinicians in early diagnosis of tumor formation. Clustering gene expression data is the most important phase, helps in finding group of genes that are highly expressed and suppressed. This paper analyses the performance of most representative hard and soft off-line clustering algorithms: K-Means, Fuzzy C-Means, Self Organizing Maps (SOM) based clustering and Genetic Algorithm (GA) based clustering for brain tumor gene expression dataset. Clusters produced by the clustering algorithms are the indications of the cellular processes. Clustering results are evaluated using clustering indices such as Xie-Beni index (XB), Davies-Bouldin index (DB), Mean Absolute Error (MAE), Root Mean Squared Error (RMSE) and Dunn's Index (DI) along with the time taken to find the compactness and separation of clusters. Experimental results prove soft clustering approaches works well to predict clusters of highly expressed and suppressed genes.

The key objective of the teaching-learning process (TLP) is to impart the knowledge to the learner. In the digital world, the computer-based system emphasis teaching through online mode known as e-learning. The expertise level of the learner in learned subjects can be measured through e-assessment in which multiple choice questions (MCQ) is considered to be an effective one. The assessment questions play the vital role which decides the ability level of a learner. In manual preparation, covering all the topics is difficult and time consumable. Hence, this article proposes a system which automatically generates two different types of question helps to identify the skill level of a learner. First, the MCQ questions with the distractor set are created using named entity recognizer (NER). Further, based on blooms taxonomy the Subjective questions are generated using natural language processing (NLP). The objective of the proposed system is to generate the questions dynamically which helps to reduce the occupation of memory concept.

No abstract

No abstract