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Muscle injuries are the most frequent cause to inability to sport exercises. The aim of any treatment is the return to the normal sport activity like before trauma. Many treatments have been purposed in the literature: recently the use of Platelet-Rich Plasma (PRP) has been described with good results. In this review all studies searched electronically using the PubMed database have been analyzed to discovery the validity, modality and efficiency of PRP injections in muscle injuries. In literature few studies are published and all of them demonstrate good results but timing, quantity, frequency and how use a PRP injection protocol remain important questions.

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