No abstract

Objective: To document the asymmetrical functional brain lesions in corticobasal degeneration (CBD) using proton magnetic resonance neurospectroscopy (MRS) and EEG cartography (EEGq). Methods: Eight patients with probable CBD were included in the study after full neurological examination and extensive neuropsychological testing, single photon emission computed tomography, anatomical x ray tomodensitometry (TDM), magnetic resonance imaging, and MRS examination. Results: MR spectra were abnormal in all seven patients in whom the examination could be completed. The EEG was also always modified in the CBD patients, and the abnormalities were enhanced by activation procedures. There was a good correlation between MRS anomalies and clinical presentation, between EEG modifications and neuropsychological patterns, and between metabolic (MRS) impairment and electrophysiological (EEG) slowing. Conclusions: These results confirm the asymmetrical features of CBD. Combined EEGq/MRS examinations at disease onset and during its subsequent course could provide strong diagnostic evidence of CBD.

No abstract

This report gives the results of dissections of the vertebrobasilar system and angio graphy of brain specimens; the technique of correct centering in vertebral angio graphy performed in patients will also be discussed. DissectionThe material consisted of 30 brain specimens. The vertebral artery was injected with plastic material as described by SALAMON (1971). Each specimen was cut at the level of the origin of the cerebral peduncles. The basilar artery was divided im mediately below the origin of the posterior cerebral arteries. Each specimen was photographed, and radiography was performed in five projections (Fig. 1), magnifica tion being used. The specimen was then dissected.The number, location, origin and termination of each vessel were carefully re corded and their frequencies in the total material calculated. ResultsThe basilar artery was present in all cases. Its course was straight in 16, curved in 10 and tortuous in 4 cases.

No abstract