Aflatoxin is a naturally occurring Mycotoxin produced by Aspergillus flavus and Aspergillus parasiticus. Aspergillus flavus is common and widespread in nature and is most often found when certain grains are grown under stressful conditions such as draught. The mold occurs in soil, decaying vegetation, hay and grains undergoing microbiological deterioration and invades all types of organic substrates whenever and wherever the conditions are favourable for its growth. Favourable conditions include high moisture content and high temperature.The aflatoxin group is comprised of aflatoxin B1,B2,G1 and G2. In addition , aflatoxin M1 (AFM1), a hydroxylated metabolite of AFB1, is excreted in the milk of dairy cows consuming an AFB1-contaminated ration. Aflatoxin B1 a prototype of the aflatoxins, is widely recognized as the most potent hepato carcinogenic compound and along with other certain members of the group, possess additional toxic properties including mutagenicity, tetrogenicity, acute cellular toxicity and it suppresses the immune system. Aflatoxin contamination of food and feed has gained global significance as a result of its deleterious effects on human as well as animal health. The marketability of food products is adversely affected by aflatoxin contamination.

Isolates of Aspergillus infected Peanuts were separately grown on modified Czapek’s medium at 280 C and the metabolites were tested for aflatoxin by HPLC. Naturally infected peanuts collected from trader’s godown were tested for aflatoxins. Aflatoxins are considered to be one of the most dangerous contaminants in food and feeds. Aflatoxins are a special group of naturally occurring metabolites produced by the fungi aflatoxins B1, B2, G1 and G2 which contaminate a variety of agricultural food and feed products .Naturally infected peanuts from Aspergillus flavus stored at trader’s godown, after several months’ storage, were found to be contaminated with aflatoxin B1.

Objectives: The present study was undertaken to provide information about bioactive compounds of Pseudoalteromonas luteoviolacea in the sea water samples collected from Rameswaram. Materials and Methods: The bioactive compounds were screened by various methods such as Gas Chromatography-Mass Spectroscopy (GC-MS), Fourier Infra Red Spectroscopy (FT-IR) and Nuclear Magnetic Resonance (NMR) spectrum activity. Results: In this study, over all 2 secondary metabolites / bioactive compounds were extracted from marine bacterial strains Pseudoalteromonas luteoviolacea. The Pseudoalteromonas luteoviolacea secrete 2 different bioactive compounds (4-(benzyloxy)-benzaldehyde and Propyl-4-Hydroxybenzoate) in the lab-scale fermentation broth. Conclusion: This study has been proven to be a profound resource on the development of natural product chemistry and upon the medical sciences. The improvement of natural products-based screening, rather than relying on synthetic sources, has been the aim of current pharmaceutical research and development. Alternative strategies to consider include the identification of potential new antibiotics from commercial crude bacterial fermentations.