The main task of thyroid hormones is controlling the metabolism rate of humans, the development of neurons, and the significant growth of reproductive activities. In medical science, thyroid disorder will lead to creating thyroiditis and thyroid cancer. The two main thyroid disorders are hyperthyroidism and hypothyroidism. Many research works focus on the prediction of thyroid disorder. To improve the accuracy in the classification of thyroid disorder this paper proposes optimization-based feature selection by using differential evolution with the Butterfly optimization algorithm (DE-BOA). For the classifier fuzzy C-means algorithm (FCM) is used. The proposed DEBOA-FCM is evaluated with parametric metric measures of sensitivity, specificity, and accuracy. In this work, the thyroid disease dataset collected from the machine learning University of California Irvine (UCI) database was used. The accuracy rate for the Differential Evolutionary algorithm got 0.884, the Butterfly optimization algorithm got 0.906, Fuzzy C-Means algorithm got 0.899 and DEBOA + Focused Concept Miner (FCM) proposed work 0.943.

Women from middle age to old age are mostly screened positive for Breast cancer which leads to death. Times over the past decades, the overall survival rate in breast cancer has improved due to advancements in early-stage diagnosis and tailored therapy. Today all hospital brings high awareness and early detection technologies for breast cancer. This increases the survival rate of women. Though traditional breast cancer treatment takes so long, early cancer techniques require an automation system. This research provides a new methodology for classifying breast cancer using ultrasound pictures that use deep learning and the combination of the best characteristics. Initially, after successful learning of Convolutional Neural Network (CNN) algorithms, data augmentation is used to enhance the representation of the feature dataset. Then it uses BreastNet18 with fine-tuned VGG-16 model for pre-training the augmented dataset. For feature classification, Entropy controlled Whale Optimization Algorithm (EWOA) is used. The features that have been optimized using the EWOA were utilized to fuse and optimize the data. To identify the breast cancer pictures, training classifiers are used. By using the novel probability-based serial technique, the best-chosen characteristics are fused and categorized by machine learning techniques. The main objective behind the research is to increase tumor prediction accuracy for saving human life. The testing was performed using a dataset of enhanced Breast Ultrasound Images (BUSI). The proposed method improves the accuracy compared with the existing methods.