Punica granatum was formerly classified under a separate family Punicaceae and recently included in Lythraceae family. The family contains genus Punica with two species Punica granatum, commonly known as Pomegranate-the predominant species and Punica protopunica the less predominant species found typically in the island of Socotra. 7 The plant is distributed throughout the world believed to be native to Iran and the Himalayan region. 8 The fruit of this plant is known as nature's power fruit. The plant is an evergreen shrub, with multiple tiny stems. It commonly grows up to 1.8 -4.6 m height. P. granatum is found to have deciduous and shiny leaves which are around 7.6 cm long. The flowers are 5 cm long normally double trumpet-shaped orangered ruffled petals and seen throughout the summer. The fruit is globose with a tough leathery skin with a diameter of around 5-7.6 cm. The mature fruit has reddish or yellowish green shiny skin. The fruit is known as a berry which is composed of spongy membranous walls which contains reddish or whitish pulp with crunchy seeds. The seeds represent around 52% of the entire mass of the fruit. [7][8][9][10] Anatomically, P. granatum can be divided into different parts like seed, juice, peel, leaf, flower, bark and root which exhibits significant pharmacological properties. 11
The present study aimed to investigate the effect of hydroalcoholic extract of Morinda tinctoria Roxb fruit on inhibition of growth and induction of apoptosis in human prostate carcinoma cells (PC-3) and lung carcinoma (A549) cells. Morinda tinctoria Roxb hydro alcoholic fruit extract (MTHFE) was taken to in vitro studies, like phytochemical screening, MTT assay, cell induced apoptosis. Dose dependant cytotoxic activities were exhibited by PC-3 cell lines and A549 cells. The result showed that, as the dose of the extract increased, the no of viable cells were found to be decreased, which confirms the anti-cancer and cytotoxic activities of the fruit extract.
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