The use of three different non-operative techniques for the treatment of female genuine urinary stress incontinence has bem assessd by objective means.One hundred and four patients complaining of stms incontinence werc allocated at random to four groups.Sixty-five per cmt of patients treated with pelvic floor exercises were significantly improved after 3 months, interfercntial therapy was effective in 32 per cent of cases. Oestrogcn treatment was initially bcncficiPl in 12 per cent of patients but rccurrcna of symptoms occurred won after stopping the treatment.The control group of patients did not show any significant changes according to perineal pad weight testing, which was used for the objective assessment of incontinence. Long tcnn follow up of these patients, after 9 months from commencing treatment still showed that pelvic floor excrciscs are the most effective nonsurgical treatment for this condition. @ lnaitute of Obstetrics and Gynaecology Trust, 1989 J Obstet Gynaecol Downloaded from informahealthcare.com by McMaster University on 02/05/15For personal use only.

No abstract

No abstract

No abstract

Najjar and Holt (1,2) have demonstrated that their fluorescent urinary pigments, F1 and F2, are related to nicotinic acid metabolism in such a way that their estimation in urine is of diagnostic use in human pellagra (1) and in canine black tongue (1,2 assessing the nutritional status of young men (7), we have investigated the conditions under which the estimation of urinary F1 and F2 might be expected to yield useful information. In particular, we sought to answer 3 specific questions: first, whether the level of these pigments in urine in a post-absorptive state agrees with the criteria of Holt (3); second, whether their excretion following administration of nicotinamide correlates with other clinical data; and third, whether their excretion following the administration of various mixtures of vitamins has the same significance as after nicotinamide alone. Our observations have been limited solely to normal young men, and we have not studied pellagrins. EXPERIMENTALWe will discuss first, analytical methods; second, the stability of F2 in urine; and third, the F1 and F2 elimination of young men under a variety of conditions. Analytical methods All estimations of F1 and F2 reported in this paper were carried out by the method of Najjar and Wood (8) or by a modification of this method for rapid field use to be described in a forthcoming paper (7). This modification is different from the method of Huff and Perlzweig (9). In our determination, fluorometry was either photoelectric or visual and the reference standards were either quinine or thiochrome.Stability of F2 in urine Field surveys sometimes necessitate the collection of specimens in climatic extremes, transportation over considerable distances, and storage for various lengths of time before -analysis. The stability of F2 under simulated field conditions was therefore investigated. Random samples of urine were collected from several normal 714