This paper presents a procedure to numerically analyze the coupled electro-structural response of laminated plates with orthotropic fiber reinforced layers and piezoelectric layers using the generalized finite element method (GFEM). The mechanical unknowns, the displacements, are modeled by a higher order shear deformation theory (HSDT) of the third order, involving seven generalized displacement functions. The electrical unknowns, the potentials, are modeled by a layerwise theory, utilizing piecewise linear functions along the thickness of the piezoelectric layers. All fields are enriched in the in-plane domain of the laminate, according to the GFEM, utilizing polynomial enrichment functions, defined in global coordinates, applied on a bilinear partition of unities defined on each element. The formulation is developed from an extended principle of Hamilton and results in a standard discrete algebraic linear motion equation. Numerical results are obtained for some static cases and are compared with several numerical and experimental results published in the literature. These comparisons show consistent and reliable responses from the formulation. In addition, the results show that GFEM meshes require the least number of elements and nodes possible for the distribution of piezoelectric patches and the enrichment provides more flexibility to reproduce the deformed shapes of adaptive laminated plates.