Abstract The anticancer active compound, cis-dichloro-diammine platinum (II), and the biomolecules cytosine and thymine form paramagnetic complexes in aqueous solution. The electron spin resonance spectra which can be attributed to paramagnetic platinum, exhibit large anisotropy in frozen solution as well as in liquid solution. This fact can be explained by assuming poly-meric structures also in liquid solution.

Abstract The ESR spectra of novel paramagnetic comple-xes between cis-dichlorodiammineplatinum(II) and cytosine or cytidine in aqueous solution are presented and discussed. The results imply a complex containing a binuclear metal-metal bonded platinum moiety with an unpaired electron spin delocalized over the dz2-orbitals.

Abstract cts-Dichlorodiammine platinum(II), which is known to be an active anticancer compound, and tryptophan form paramagnetic complexes in aqueous solution. These can be detected by means of electron spin resonance spectroscopy (ESR) after a reaction time of several hours. The ESR spectra are interpreted to be due to Pt(III) in a low spin d7 configuration. The optical results obtained are in accordance with the assumption of columnar structures of the paramagnetic complexes

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