In this work, chromizing coating was prepared on P110 oil casing tube steel by means of plasma surface chromizing to improve its surface performance and prolong its service lifetime. Electrochemical experiments, including open circuit potential (OCP) and potentiodynamic polarization were conducted in CO2-saturated simulated oilfield brine to exam the corrosion resistance of the chromizing coating. Wear resistance of the chromizing coating was investigated using reciprocating type tribometer under dry sliding against GCr15 steel counterpart. The experimental results obtained herein revealed that chromizing coating was uniform and compact; the obtained coating exhibited higher open circuit potential and lower corrosion current density in comparison to P110 steel. Chromizing coating with higher surface hardness showed better wear resistance than that of P110 steel. Subsequently, plasma surface chromizing could be considered as a potentially effective method for improving the surface performance of P110 steel.