Microwave Mediated Organic Synthesis (MMOS) is typical on the proficient heat shift carried out by dielectric heating, which in turn, is primarily dependent on the capability of the reagent or solvent to take up microwave energy. The employment of microwave energy has witnessed a fast expansion in the past two decades, with novel and pioneering applications in peptide and organic synthesis, material sciences, polymer chemistry, biochemical processes and nanotechnology. This review summarizes current MW- mediated catalytic reactions in use for the synthesis of a diversity of N-heterocycles by Multi-Component Reactions (MCRs) and a variety of miscellaneous reactions. Also, the review addresses some aspects of the use of nanoparticles for a diversity of applications in microwave chemistry.

In recent times, synthetic organic reactions have gained significant attention as they are becoming a versatile tool in the synthesis of pharmaceuticals, agrochemicals and their intermediates. Sulfamic acid (SA) is an acid catalyst that demonstrated high efficiency in various organic transformations that will be highlighted in this review. These include efforts to develop green approaches using SA catalyst for the CÀ C bond formation reactions and functional group trans-formations, as well as the synthesis of various OÀ and Nheterocyclic compounds and other miscellaneous reactions including multicomponent reactions. The easy recovery (for subsequent reuse) of the catalyst by filtration without the need for solvents is an important advantage of SA catalyst. In this review, SA promoted greener methodologies that were developed and the applicability of these methodologies are addressed.

The fused Nitrogen heterocyclic compounds and their derivatives have grown in prominence over the past several decades as a result of their significant medical value. The adaptable and easily synthesized N-Heterocyclic scaffolds are particularly exciting in both synthetic organic chemistry and the biological sector due to their powerful pharmacological properties, which are taken into consideration while considering their numerous uses. For the synthesis of N-heterocycles and their derivatives, several attempts were undertaken to create a variety of synthetic protocols. The N-Heterocyclic compounds provide a variety of adaptable structures for specific biological applications and represent novel, broad-spectrum antibacterial and anticancer agents. They typically have minimal toxicity profiles. The majority of these N-Heterocycles have demonstrated more cytotoxicity than the effective anticancer medication cisplatin. The design, synthesis, structural characterisation, and biological uses of N-Heterocycles are reviewed in this work. In this article, the developments made in this specific field are comprehensively examined.