Objective:This study was designed to evaluate the anti-inflammatory and antipyretic activity of ethyl acetate extract of Vitex leucoxylon Linn. in various animal experimental models.Materials and Methods:Ethyl acetate extract of V. leucoxylon Linn. evaluated for anti-inflammatory activity in carrageenan, mediator-induced rat paw edema, and cotton pellet-induced granuloma model. The antipyretic activity was evaluated by yeast-induced pyrexia model.Results:Single administration of the ethyl acetate extract of V. leucoxylon Linn. at dose of 500 mg/kg p.o. showed significant (P < 0.001) inhibition of rat paw edema. The ethyl acetate extract showed significant antipyretic activity in brewer yeast-induced pyrexia in rats throughout the observation period of 4 h.Conclusion:This study shows that ethyl acetate extract of V. leucoxylon Linn. has significant anti-inflammatory and antipyretic activity.

Herbal immunity boosters are the medicinal plants which increase the immunity of the human body and make the body able to fight with the various diseases. These immunity boosters are serving as a boon in the case of coronavirus disease. COVID-19 affects our respiratory system and lowers the immunity of the patient and the persons having weak immunity have the more chances to get affected with the diseases. Tulsi, garlic, ginger, giloy, coconut oil, turmeric, ashwagandha, amla, black pepper, aloevera are the herbal immunity boosters. These herbal drugs used traditionally in medicines and also proved effective in scientific studies.  The regular consumption of these boosters helps to treat the mild to moderate symptoms of diseases at home. Keywords: Herbal immunity boosters, Coronavirus, COVID-19, Garlic, Tulsi, Ginger, Aloe vera