Introduction:Coping mechanism and adaptation skills play an important role in successfully adjusting to breast cancer. The concept of psychological immunity integrates different coping skills that are capacities leading to successful adaptation. Hypnosis as a psychological intervention is effective in increasing coping potentials; nevertheless, there is little empirical evidence on the effectiveness of hypnosis in terms of increasing psychological immunity. Purpose: Our aim was to examine the characteristics and changes of psychological immune competence of breast cancer patients receiving different psychological interventions. Methods: Altogether 61 patients were assigned to receive hypnosis, music, and special attention as adjunctive treatments to standard chemotherapy. Psychological immunity was measured four times with Psychological Immune Competence Inventory (PICI). Results: Differences were detected during treatment on