Hypertensive disorders of pregnancy remain a leading cause of maternal and perinatal morbidity and mortality. The management of severe gestational hypertension and preeclampsia at term is clear. The only definitive treatment for the same is delivery. 1 But the management of mild gestational hypertension without any other complication at term is not clear. Induction of labour is thought to prevent the progression of hypertension and its complications like eclampsia, HELLP syndrome, placental abruption, renal failure etc. but doing so could increase the instrumental and caesarean delivery rates. The HYPITAT trial done on 756 patients with gestational
A 28-year-old multiparous lady presented to the Gynaecology outpatient department with a 12 × 5 cm warty growth in the vulva. A biopsy of the growth revealed condyloma acuminata of the vulva. Simple vulvectomy was done. A PCR of the specimen detected the presence of human papilloma virus (HPV)-16 which is usually considered as a high-risk HPV type for carcinogenesis.
It is not clear how often epithelial tumours affect young women. This study aimed to evaluate the clinico-pathological pattern and survival outcome of women, 40 years and younger, with cancer ovary. Women 40 years and younger, operated between 2008 and 2012 for ovarian cancer, were retrospectively recruited and followed up. The study design was descriptive as well as a survival analysis. A hybrid of retrospective and prospective cohort design was used for risk factor analysis. Of the 115 women less than 40 years being operated for probable ovarian cancer, 22 were excluded for various reasons. Demographic details, clinical presentations, histopathological features, treatments and survival outcomes were studied. The primary outcomes looked for were death and recurrence. Secondary outcomes were complications of treatment and fertility. The predominant histology in the study population was epithelial tumour (70%), and serous adenocarcinoma was the commonest tumour type. The overall survival rate was 87%, and progression free survival was 63%. Time to death and recurrence were dependent on stage of disease, histology of tumour, primary treatment and residual disease at surgery. In multivariate analysis, the hazard ratio for recurrence in advanced stages was 12.6 (95% CI 3.5 to 45.5; < 0.001) as compared to early stage disease. Epithelial ovarian cancers are common in young women. Death and recurrence are more likely in women with epithelial cancers, advanced stage disease and in those with residual tumour at cytoreductive surgery.
We report an uncommon case of primary ovarian leiomyoma with torsion. Leiomyoma of the ovary is an extremely rare benign solid neoplasm of uncertain etiology. Our patient presented with abdominal pain and imaging showed right adnexal solid mass. All tumour markers except LDH were normal. The patient underwent laparotomy proceed right salpingo-ophorectomy. Intraoperatively, it was found to be twisted right ovarian solid tumour and histopathological examination revealed leiomyoma of ovary.
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