Adverse effects observed in 300,000 medical laser hair removal sessions between June 1998 and April 2014 have been indirectly surveyed. The small number of adverse effects and their resolution with no significant sequelae is confirmed. Laser hair removal is a safe and effective method, but it is not risk-free. It is clearly necessary to i) strictly update the patient's medical history at each session, ii) duly train healthcare staff, and iii) follow the applicable safety protocols. Note that data collection was based on the memory of the treating team, which means that significant bias is likely. However, bias will be high for mild adverse effects but very low for serious adverse effects (which have also required follow-up). The conclusions of this work may only be applicable to the moderate and serious adverse effects of laser hair removal, but not to standard, mild adverse effects.

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Background Quantification of regional myocardial function allows risk stratification in heart disease. CMR tagging (TAG) enables the evaluation of segmental cardiac deformation, but it has not reached clinical routine due to the long acquisition and post-processing times. Conversely, CMR feature-tracking (FT) is a post-processing method based on standard cine-MR imaging. Purpose To compare myocardial strain and torsion obtained with CMR-TAG and CMR-FT in healthy volunteers and myocardial infarction (MI). Methods 42 subjects (18 healthy; 24 MI) underwent CMR (1.5T, cine/TAG sequences). Global and segmental (16-segment) circumferential strain (CS), and torsion were measured using FT (CVI42, Canada) and tagging (InTag, France). Inter-method agreement was assessed using 2-way-mixed intraclass correlation coefficient (ICC). Results The agreement for segmental and global CS measurements was good to excellent in both groups (Table). Torsion angle showed excellent (0.763) and good (0.697) agreement for healthy and MI. Conclusion CMR-FT strain and torsion measurements showed high agreement with CMR-tagging. Thus, CMR-FT provides a potential clinical alternative in the assessment of regional ventricular function. Funding Acknowledgement Type of funding source: Public grant(s) – National budget only. Main funding source(s): Carlos III Health Institute, Spanish Ministry of Economy and Competiveness; Agencia Valenciana de la Innovaciόn, Generalitat Valenciana

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