http://hyper.ahajournals.org/ Downloaded from Dong et al Effects of Air Pollution on Blood Pressure 579pollution on BP in different parts of the world are unclear but may result from spatial and temporal variability in pollution sources and composition. 17,18 Compared with short-term effects of air pollution, there is little information on the relation between chronic exposure to air pollution and prevalent hypertension. Inconsistent results have also been reported on the association between incident hypertension and air pollution. For instance, Coogan et al 19 showed in a 10-year follow-up for incident hypertension and diabetes mellitus of black women from Los Angeles that NO X (but less PM 2.5 ) borderline increased the risk of becoming hypertensive. However, Sørensen et al 20 reported that longterm exposure (1 and 5 years) to NO X was not associated with incident self-reported hypertension in a Danish cohort. We hypothesized that at the population level, long-term exposure to ambient air pollution is associated with higher BP and higher prevalence of hypertension among humans. In this study, we tested this hypothesis in the 11 Districts Chinese Study, a cross-sectional study of air pollution and adult health in a large, well-characterized population-based sample, residing in northeast China, where there are wide differences in inter-and intracity gradients and ambient pollutant levels, offering a valuable opportunity to assess the associations between exposure and response. Methods Study Cities Selection and Subject RecruitmentMore than 20 million people reside in 14 cities in Liaoning province in northeast China. To maximize the inter-and intracity gradients of the pollutants of interest and minimize the correlation between district-specific ambient pollutants, in April 2009, we selected 3 cities (Shenyang, Anshan, and Jinzhou) based on the results of air pollution measurements between 2006 and 2008. There are 5, well-identified geographic districts in Shenyang, and 3 districts in Anshan and Jinzhou, respectively. Three communities within 1 km of air-monitoring sites were randomly chosen from these districts resulting in 33 locales, and from each of these, 700 to 1000 households were randomly identified. One participant, aged 18 to 74 years, was selected from each household without replacement. Our entry criterion was that the subject should have lived at that place for at least 5 years. The design and conduct of this investigation was reviewed and approved by Human Studies Committee of China Medical University. Before data collection, a written informed consent form was obtained from each participant. Ambient Air PollutionIn each of the selected study districts, there was only 1 municipal air pollution monitoring station, which was located 1 mile from the participants' homes. Measurements of PM 10 , SO 2 , NO 2 , and O 3 concentrations from 2006 to 2008 were obtained at the stations. The measurements were subject to uniform criteria for monitoring, siting, instrumentation, and quality assurance. Thes...

Wandering away from home, or elopement, is a behavior that places persons with dementia at risk of serious injury and may lead family caregivers to place their loved ones in institutions or to severely restrict their independence. Funding from the National Institute on Aging (NIA) was used to evaluate the Mobile Locater, an electronic device designed to help caregivers quickly locate a person who has eloped. This 6-month pilot study included case studies of seven users and an opinion survey of family caregivers, professional caregivers and search and rescue workers. The survey results showed that respondents were positively impressed by the device, only identifying cost as a potential drawback. Case studies revealed that the equipment was easy to use, effective, and helpful to caregivers' peace of mind. These results suggest that the Mobile Locater is a valuable tool deserving of further study.

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This study evaluated the impact of intergenerational activities on elders' engagement and expressiveness levels in two settings. Study 1 was conducted with 22 well elders at a senior center and approximately 15 children from a nearby grade school. Data were collected using a momentary time sampling procedure, and inter-observer reliability averaged 88% (ranging from 78% to 97%). Elders were significantly more engaged (t (85) = 4.60, p > .001) and expressive (t (85) = 5.55, p > .001) in the treatment condition than the control condition. Study 2 was conducted with 25 older adults diagnosed with dementia, living in a special care unit. Twenty-eight second-graders were in the experimental group and 32 second-graders were in the comparison group. A momentary time sampling procedure was used to observe engagement, expressiveness, and inappropriate behavior levels. Inter-observer agreement averaged 94% (ranged from 85% to 100%). Elders were significantly more engaged in the structured activities with children than the structured activities without children, and significantly more engaged in structured activities without children than the no-activity condition, F(1) = 60.1; p > .01. Elders were also significantly more expressive in structured activities with children than the structured activities without Pamela K. Xaverius is a consultant epidemiologist,

Background: Little information exists on whether gender or asthma status modifies the effects of secondhand smoke (SHS) exposure on lung function. Objective: To evaluate whether gender or asthma status modifies the association of SHS exposure with lung function. Methods: A total of 6,740 children (average 11.6 years) were recruited from 24 districts of 7 cities in northeast China in 2012. SHS exposure included exposure to environmental and maternal smoking both in utero and during early childhood (postnatal). Lung function was measured using electronic spirometers. Two-step regressions were used to analyze the association between SHS and lung function. Results: In utero and postnatal exposure to SHS was independently associated with decreased lung function in both genders; however, this association was greater among males. For example, when exposed to maternal smoking during pregnancy, the adjusted odds ratio (aOR) for decreased forced vital capacity (FVC) was 6.46 (95% confidence interval [CI]: 2.58-16.17) among males, while only 2.16 (95% CI: 0.96-4.88) among females. More positive associations between SHS exposure and decreased lung function were detected among nonasthmatic compared with asthmatic children. Nonasthmatics had significantly larger deficits from in utero exposure to maternal smoking, which concerned decreased lung FVC function (aOR = 2.58, 95% CI: 1.28-5.21) and decreased lung forced expiratory volume in 1 s (FEV1) function (aOR = 2.32, 95% CI: 1.01-5.33). A similar pattern was also observed for the associations between SHS exposure and continuous pulmonary function test measurements. Conclusions: SHS exposure was associated with decreased lung function. Males and nonasthmatics seem to be more susceptible than their respective counterparts.