Backgrounds: Breast cancer is the uncontrolled growth of breast cells. The number of new breast cancer cases reached 68,858 cases (16.6%) of the total 396,914 new cancer cases in Indonesia, while the number of deaths reached 22 thousand cases. The rate of breast cancer in Bali ranks first in the most common types of cancer in women. aim: Knowing the characteristics and clinical features of breast cancer patients at the Sanjiwani General Hospital in Gianyar from January to December 2021. Methods: This study uses a descriptive design to describe or make a description of a condition or situation objectively. This study will use secondary data from medical records at the Sanjiwani Hospital Gianyar, including age, parity, family history, menopausal status, chief complaint, tumor size, metastasis, histopathological type, and breast cancer subtype. Data analysis used univariate data. Results: 116 confirmed breast cancer patients mean age 49.85±9.89 years, multipara 75.9%, without a family history, 97.4%, premenopausal and menopause status are the same, most complaints are lumps 45.7%, T4 size 55.2 %, lymph nodes with positive nodules 71.6%, without metastases 91.4&, typeInvasive carcinoma of no special type grade 2 38.8%, and luminal subtype B Her 2- 37.9%. Conclusion: Most of them are middle-aged, without a family history, with complaints coming because of lumps, T4 size with positive nodules without metastases, most are Invasive carcinoma of no special type grade 2 and subtypeLuminal B Her 2 (-).

Introduction: Currently, prognostic determination of breast cancer often posed a challenge to oncologists due to variability in many molecular processes and metabolism. Caveolin-1 is caveolae protein that is closely related to tumour metabolism and had been proved to be associated with the level of malignancy in pre-clinical studies, but there is still no clinical evidence about Cavolin-1. Therefore, this study aimed to evaluate the association between the expressions of Caveolin-1 with clinicopathological characteristics of breast cancer.Methods: An analytical cross-sectional study was conducted in Sanglah General Hospital and Biochemistry Laboratory by using 78 subjects. The clinicopathological characteristics were recorded from medical records while Caveolin-1 expression was determined by IHC.Results: Caveolin-1 expression was found to be significantly associated with clinical stadium, subtype, histological grade and LVI in bivariate analysis. Multivariate analysis found significant only in three of them with high expression of Caveolin-1 was associated with early stadium, negative LVI and Luminal A subtype.Conclusion: Caveolin-1 expression is significantly associated with clinical stadium, LVI and subtype in breast cancer with high expression often delineate early stage, negative LVI and luminal A subtype.