Background:The knee joint is the largest and the most complex joint of the human body. It is not covered by any thick muscular covering anteriorly.Objectives:The purpose of this study was to explore the diagnostic capabilities of clinical examination, magnetic resonance imaging (MRI), and arthroscopy in traumatic disorders of the knee joint, to seek correlation between clinical findings, MRI findings and arthroscopic.Patients and Methods:A total of 26 patients with a presentation suggestive of traumatic knee pathology were studied prospectively. A detailed history was taken and relevant clinical examination was done, which was followed by MRI of the knee. The patients were scheduled for arthroscopy under general/spinal anesthesia, whenever indicated.Results:Keeping arthroscopic examination as standard, the correlation between clinical and arthroscopy showed a sensitivity of 80%, specificity of 86%, accuracy of 63.16%, negative predictive value of 93.48%; whereas MRI vs. arthroscopy showed a sensitivity of 74.42%, specificity of 93.10%, accuracy of 84.21%, and negative predictive value of 88.04%.Conclusions:The clinical examination is an important and accurate diagnostic modality for evaluation of traumatic derangement of the knee joint. It is noninvasive, easy, available, and valuable diagnostic modality. The MRI is an accurate diagnostic modality. It can be used whenever there is an uncertain indication for arthroscopy. However, costs have to be kept in mind, especially in patients with low socio-economic status.

The success of dental implants depends primarily on the primary implant stability and the bone density so that predictable osseointegration can be achieved. To achieve the desired results, systematic preoperative planning for implant placement is required. The sole aim of the study was to assess the reliability of preoperative bone density of mandibular posterior region for implant placement using computerized tomography-derived bone densities in Hounsfield units (HU). A total of 200 patients with 352 implant sites between 2014 and 2017 were assessed for the posterior mandibular area using cone-beam computed tomography (CBCT). Evaluation was done by two experienced observers independently. The mean bone density of males was 690.5 ± 104.12 HU and in females, it was 580.20 ± 120.2 HU. Overall, 21% of sites were of low bone density, 39.5% were of intermediate density, and 39.4% were of high density. Receiver operating characteristic (ROC) analysis presented that the CBCT intensity values had a high predictive power for predicting both high-density sites and intermediate-density sites. We can say from our results that, for predicting the bone densities in posterior mandible for determining implant sites, so as to achieve best osseointegration, CBCT values can be reliably used. It has been proved that bone density and implant stability are dependent on each other and osseointegration is important for the success of treatment. With advancements in dentistry and introduction of CBCT, treatment planning and prediction of appropriate implant sites could be made easy and more predictable. Thus, we can say that CBCT can be considered an alternative diagnostic tool for the bone density evaluation during treatment planning for implant placement. Bone density, Cone-beam computed tomography, Implants, Osseointegration.

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The hepatoprotective properties of the ethanolic extracts of Punica granatum peels, Crataeva religiosa leaves and Jasminum polyanthrum leaves were evaluated for the paracetamol induced liver toxicity in mice. Antioxidant, cytotoxicity and phytochemical screening were carried out to assure the therapeutic efficacy of these plants. Oral administration of plant extracts for 7 days in mice significantly reduced the impact of paracetamol toxicity on the serum markers of liver damage, aspartate transaminase (AST), alanine transaminase (ALT) and total protein. The extract showed significant hepatoprotective effects as evidenced by decreased serum enzyme activities like ALT, AST and changed total protein. The phytochemical and antioxidant studies also supported that plant extract markedly reduced the toxicity due to presence of antioxidant phytochemicals. The result suggests that Jasminum polyanthrum is potent hepatoprotective agent against paracetamol induced hepatotoxicity in mice.