Objectives: The present study was undertaken to provide the health professionals who were working at a tertiary care hospital, with a simple method to report Adverse Drug Reactions (ADRs) and to monitor, document and to evaluate them according to the set criteria.Method and Materials: This study was conducted over a period of 15 months from 1st Jan' 2008 to 31st March 2009 at Goa Medical College and Hospital (Goa, India). The evaluation of the data was done for various parameters, which included patient demographics and drug and reaction characteristics. An assessment was also done for the outcome, causality and the severity of the drug reactions.Results: A total of 265 ADRs were reported. Among the drugs, the ß-lactam antibiotics were implicated the maximum number of times (54, 20.37%), followed by fluoroquinolones (35, 13.20%), antiretrovirals (33, 12.45%) and antiepileptics (31, 11.69%). Females showed more ADRs (142, 54%) than males (123, 46%). The skin was involved in about 57.73% (153) of the ADRs, while the CNS and the vascular system were involved in 8.67% (23) and 8.30% (22) of the ADRs. Most of the ADRs were categorized as "Type II" (203, 77%) against "Type I" (62, 23%) by Rawlins and Thompson's classification. The causality assessment was done by the Naranjo Algorithm and 62.26% (165) were seen to fall in the "probable category" as compared to 29.05% (77) in the "highly probable" one. Out of all the ADRs which were reported, 34.71% (148) were "severe", in accordance with the Modified Hartwig and Siegel's scale. Conclusion:The present work was a humble attempt to set up a well organized ADR reporting system at our government hospital. The systematic tracking and monitoring of ADRs can shed light on their extensiveness and their patterns of occurrence.

A chillum consist a mixture of Cannabis and tobacco.Cannabis, also known as marijuana; it is a psychoactive drug from the Cannabis plant intended for medical or recreational use; nowadays widely being abused for getting high and temporary relaxation. Sputum examination of chillum smokers may indicate harmful effects of chillum smoking on lungs. Objectives of present study were to study the sputum characteristics and differential cell count of chillum smoking Sadhus of Kumbh Mela. Present descriptive observational study was conducted among fifty Sadhus of Kumbh Mela of Nashik. Participants were selected using purposive sampling method. In present study all sputum samples showed raised differential cell count and statistically significant association was observed between differential cell like Neutrophils, Lymphocytes and Macrophages with different content present in chillum.

Background: Our knowledge on reasons of non-acceptance and complication to H1N1 Vaccination by health care workers is limited. A better understanding of factors having significance in vaccine acceptance is crucial. With this background in mind present study was conducted at tertiary care centre to determine the Acceptance, Compliance, and Complication of anti-H1N1 seasonal vaccine among Health Care Workers (HWCs). Materials and Methods: Prospective Observational study was conducted to observe the rate of acceptance, compliance and complications of anti H1N1 seasonal vaccine among 100 health care workers in the period of December 2015 to December 2017 in Tertiary Health Care Centre. All participants were counselled 3 times at interval 6 months (0, 6, and 12 months) regarding H1N1 vaccine. Result: Vaccine acceptance rate among health care workers was only 03% before counseling. The main cause for not acceptance of vaccination was fear of adverse effects reported by 27% health care workers followed by cost of vaccine (12%) and work pressure (10%) or nonavailability of time. Conclusion: As counseling sessions progressed health care workers also started accepting vaccination. After completion of third counseling session rate of vaccine acceptance increased from 3% to 71% and also negative and doubtful conception of health care workers were and changed completely. After counseling their knowledge regarding influenza vaccine was increased. Even though some post vaccination complications had been reported by recipient; those symptoms lasted for short duration of time and there was no serious adverse effect of H1N1 vaccine.

Background: Our knowledge on reasons of non-acceptance and complication to H1N1 Vaccination by health care workers is limited. A better understanding of factors having significance in vaccine acceptance is crucial. With this background in mind present study was conducted at tertiary care centre to determine the Acceptance, Compliance, and Complication of anti-H1N1 seasonal vaccine among Health Care Workers (HWCs). Materials and Methods: Prospective Observational study was conducted to observe the rate of acceptance, compliance and complications of anti H1N1 seasonal vaccine among 100 health care workers in the period of December 2015 to December 2017 in Tertiary Health Care Centre. All participants were counselled 3 times at interval 6 months (0, 6, and 12 months) regarding H1N1 vaccine. Result: Vaccine acceptance rate among health care workers was only 03% before counseling. The main cause for not acceptance of vaccination was fear of adverse effects reported by 27% health care workers followed by cost of vaccine (12%) and work pressure (10%) or nonavailability of time. Conclusion: As counseling sessions progressed health care workers also started accepting vaccination. After completion of third counseling session rate of vaccine acceptance increased from 3% to 71% and also negative and doubtful conception of health care workers were and changed completely. After counseling their knowledge regarding influenza vaccine was increased. Even though some post vaccination complications had been reported by recipient; those symptoms lasted for short duration of time and there was no serious adverse effect of H1N1 vaccine.