In present scenario cases of infertility arise abundantly which is a serious problem among the present generation as it affects the person mentally hence can deteriorate life. There are various etiological factors related to male infertility. In Ayurveda the quality of Shukra is mentioned by various Acharya to produce a healthy progeny. But Shukra Dushti can lead to differently abled or no progeny. There are various types of Shukra Dushti mentioned by Acharya Sushrut, Ksheena -Shukra is one of them. Aim: To compare the efficacy of Virechana Karma followed by Ashwattha Churna and Ashwattha Churna alone in Ksheena Shukra (oligozoospermia). Objective: To assess the efficacy of Virechana Karma followed by Ashwattha Churna in Ksheena Shukra and to assess the efficacy of Ashwattha Churna alone in Ksheena Shukra and to detect increase in sperm count. Methods: It is open label, randomized, interventional and comparative study. Group A - In this group Virechana Karma followed by Ashwattha Churna was given. Group B - In this group Ashwattha Churna was given. Result: Group A (Virechana Karma followed by Ashwattha Churna) there was an increase of 55% in sperm count, increase of 11.6% in sperm motility, relief in Maithuna Ashakti is 50%, relief in Medra Vrishna Vedana is 32%, and relief in Chiraat Prashek is 32%. Conclusion: Both group shows statistically significant results in parameters i.e., Maithuna Ashakti, Medra Vrishna Vedana, Chiraat Prashek, sperm count, motility.

The main cause of a childless couple's lack of societal support is the depressing ignorance and maltreatment of the causes of childlessness and its treatment. Childless couples are socially and emotionally vulnerable in many parts of the world because of this isolation. The pressure to become pregnant may be directed at women in various societies, and she is frequently the one who suffers the most from its effects. One of the primary reasons for male infertility is low sperm count (oligozoospermia), which is associated with Ksheena Shukra (oligozoospermia). Before administering Vajikarana medications, Shodhana procedures must be carried out, especially because Virechana Karma has been recommended in cases with Shukra Dushti [1].