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Rare-earth (RE) analogues of UiO-66 with non-functionalised 1,4-benzenedicarboxylate linkers are synthesised for the first time, and a series of synthetic approaches is provided to troubleshoot the synthesis. RE-UiO-66 analogues are...

MOFs as green materials – a highlight of the environmentally conscious or “green” applications of MOFs.

Background The aim of this study was to investigate how the COVID-19 pandemic influenced ERAS program application in colorectal surgery across hospitals in the Lazio region (central district in Italy) participating in the “Lazio Network” project. Methods A multi-institutional database was constructed. All patients included in this study underwent elective colorectal surgery for both malignant and benign disease between January 2019 and December 2020. Emergency procedures were excluded. The population was divided into 2 groups: a pre-COVID-19 group (PG) of patients operated on between February and December 2019 and a COVID-19 group (CG) of patients operated on between February and December 2020, during the first 2 waves of the pandemic in Italy. Results The groups included 622 patients in the PG and 615 in the CG treated in 8 hospitals of the network. The mean number of items applied was higher in the PG (65.6% vs. 56.6%, p < 0.001) in terms of preoperative items (64.2% vs. 50.7%, p < 0.001), intraoperative items (65.0% vs. 53.3%, p < 0.001), and postoperative items (68.8% vs. 63.2%, p < 0.001). Postoperative recovery was faster in the PG, with a shorter time to first flatus, first stool, autonomous mobilization and discharge (6.82 days vs. 7.43 days, p = 0.021). Postoperative complications, mortality and reoperations were similar among the groups. Conclusions The COVID-19 pandemic had a negative impact on the application of ERAS in the centers of the “Lazio Network” study group, with a reduction in adherence to the ERAS protocol in terms of preoperative, intraoperative and postoperative items. In addition, in the CG, the patients had worse postoperative outcomes with respect to recovery and discharge. Supplementary Information The online version contains supplementary material available at 10.1007/s00268-022-06694-8.

Metal–organic frameworks (MOFs) are traditionally synthesized using formamide solvents [e.g., dimethylformamide (DMF) and diethylformamide (DEF)] that are hazardous to human health and the environment and also made from fossil fuels. In order to alleviate the environmental impact of MOF synthesis in both academic and industrial settings, safer and greener solvent alternatives are desired. Herein, STEPOSOL MET-10U (N,N-dimethyl-9-decenamide), a bioderived solvent produced via olefin metathesis using renewable feedstocks, such as plant oils, is explored as a solvent for the synthesis of a series of structurally diverse MOFs. The MOFs synthesized using STEPOSOL MET-10U are characterized by powder X-ray diffraction, nitrogen adsorption–desorption analysis, scanning electron microscopy, proton nuclear magnetic resonance spectroscopy, diffuse reflectance infrared Fourier transform spectroscopy, and thermogravimetric analysis, displaying high crystallinity, purity, porosity, and thermal stability, consistent with the materials typically synthesized in DMF.