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The Allen Brain Atlas (ABA) provides a similar gene expression dataset by genome-scale mapping of the C57BL/6J mouse brain. In this study, the authors describe a method to extract the spatial information of gene expression patterns across a set of 1047 genes. The genes were chosen from among the 4104 genes having the lowest Pearson correlation coefficient used to compare the expression patterns across voxels in a single hemisphere for available coronal and sagittal volumes. The set of genes analysed in this study is the one discarded in the article by Bohland et al., which was considered to be of a lower consistency, not a reliable dataset. Following a normalisation task with a global and local approach, voxels were clustered using hierarchical and partitioning clustering techniques. Cluster analysis and a validation method based on entropy and purity were performed. They analyse the resulting clusters of the mouse brain for different number of groups and compared them with a classically-defined anatomical reference atlas. The high degree of correspondence between clusters and anatomical regions highlights how gene expression patterns with a low Pearson correlation coefficient between sagittal and coronal sections can accurately identify different neuroanatomical regions.

The seminal levels of estrone (El), estrone sulphate (E,S), and estradiolLl7j3 (E2) were measured simultaneously after a chromatographic step in the semen samples of 79 men, including fertile volunteers, vasectomized subjects, and patients with oligozoospermia and secretory azoospermia. E,S concentrations in seminal plasma were higher than in serum (with a semeniserum ratio of approximately 2). Seminal El and E,S levels in oligozoospermic subjects were significantly decreased compared to controls (p < 0.02 and p < 0.03, respectively). The seminal E,S concentration was significantly reduced in azoospermic patients (p < 0.02) and to a greater extent in vasectomized subjects (p < 0.001). As seminal EIS is likely to be mainly of testicular origin, the decreased seminal E,S levels in oligoazoospermia are an index of impaired testicular function.

Kingship in early medieval Kāmarūpa (Assam) was influenced by the collision of orthodox and heterodox Brahmanic traditions with various tribal cultures. Since the last part of theŚālastambha period (seventh-tenth century) the royal tutelary deity of Kāmarūpa was the menstruating Kāmākhyā, an ancient kirāta goddess. According to the Puranic tradition, the cult of Kāmākhyā was absorbed within Hindu religious folds by the mytho-historical king Naraka of Kāmarūpa. According to textual and epigraphic records, Naraka was conceived by Pr . thvī (Earth goddess) during her menstrual period, through a sexual intercourse with varāha (boar form of Vis . n . u). All early medieval dynasties of Kāmarūpa traced back their origins to Naraka, connecting their lines to the divine power but also to the menstrual blood-a substance considered extremely impure though powerful in Vedic and post-Vedic traditions. The king operated as a cross-cultural mediator: he was the only actor who was able to harness the produced polluted forces, through the Tantric rituals, in order to strengthen the political power. Thence, this essay aims to demonstrate, through inter-and intra-textual evidences, epigraphic records, and ethnographic data, that in Assam throughout the early medieval ages, the kingship grounded its roots in an osmotic cross-cultural process which was influenced by tribal traditions and orthodox and heterodox Hindu sects.

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