Carotid-radial pulse wave velocity (PWV) decreases in normal healthy individuals following hyperemia provoked by release of arterial cuff occlusion. To determine the effects of specific cardiovascular (CV) risk factors on the hyperemic PWV response, we measured PWV before and after brachial artery (BA) occlusion in 218 participants (66% males, age 56 +/- 19 years), with and without CV risk factors/disease. DeltaPWV ranged from -46% to +35% and values were normally distributed. On univariate analyses, DeltaPWV correlated with age, hypertension (Htn), hypercholesterolemia, diabetes mellitus (DM), coronary disease, congestive heart failure (CHF), smoking, and mean arterial pressure (MAP). On multivariate analysis, DeltaPWV was independently related to Htn (B = 4.56, P = .03) and CHF (B = 7.34, P = .008) and trended toward a higher MAP (B = .113, P = .067), DM (B = 4.01, P = .11), and hypercholesterolemia (B = 3.36, P = .12). In conclusion, hyperemic changes in carotid-radial PWV values are independently related to Htn and CHF and possibly DM and hyperlipidemia.

No abstract

Background: The arterial stiffness is well established pulse parameter in modern science and has shown significant results in assessing the cardio vascular risks such as diabetes. The association of arterial stiffness measured from Tridoshas with diabetes is not established in Ayurveda. Objective: The aim of this study is to investigate the association of arterial stiffness measured from Tridoshas with Type 2 diabetes. Materials and Methods: A total of 192 participants were included in this study. The pulse data was collected from Tridosha locations using Nadi Tarangini. The arterial stiffness parameters, stiffness index (SI) and reflection index (RI) were considered for the study. The participants were divided into two groups based on fasting plasma glucose (FPG) as defined by American Diabetes Association. The SI and RI were measured from Tridoshas and studied across diabetes and non-diabetes groups. Results: The SI at vata was negatively correlated with FPG (p < 0.05) for non-diabetes group whereas for diabetes group there was no significant correlation. The RI was not significantly correlating with FPG. There was a significant positive correlation between SI and RI (p < 0.01). The SI at vata was significantly higher in diabetes group (5.898 ± 0.786) compared to non-diabetes group (5.414 ± 1.179), SI at pitta was significantly low in diabetes group (7.308 ± 1.929) compared to non-diabetes group (8.726 ± 3.474) and SI at kapha was significantly low in diabetes group (6.529 ± 1.389) compared to non-diabetes group (6.529 ± 1.389). Conclusion: The results confirmed that the arterial stiffness measured from Tridoshas is significantly varying across diabetes and non diabetes groups.