In this paper introduces a PV based generation system interlinked with shunt active power filter (SAPF) to provide the effective reactive power compensation and mitigation of harmonics. The SAPF is comprised of a photovoltaic generation system, DC link capacitor and voltage source inverter (VSI). The current harmonics caused by nonlinear loads can be greatly reduced with the help of active power filter. To generate the reference current and the regulation of SAPF, the artificial neural network is proposed. The Second Order Generalized Integrator (SOGI) with Artificial Neural Network (ANN) controller is engaged to calculate the reference source current for SAPF. ANN additionally boasts great compatibility for digital implementation, control performance, and lightning-fast dynamic reaction. To demonstrate the effectiveness and superior concert of the proposed methodology, the designed controller is validated with the help of MATLAB simulations.