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Background: The most striking change in adolescent girls is the onset of menstruation. After menarche, common menstrual abnormalities that the female adolescent may encounter include premenstrual syndrome, dysmenorrhea, prolonged menstrual bleeding, and emotional disturbances, In present study, we evaluated gynaecological problems of adolescent girls attending outpatient gynaecology department at tertiary care centre. Material and Methods: Present study was prospective, observational study, conducted in adolescent girls (10-19 years age) attending to the outpatient department of Obstetrics and gynaecology suffering from various gynaecological problems, willing to participate. Results: During study period, total 396 adolescent girls visited gynaecology outpatient department were considered for present study. Most cases belonged to 17-19 years age (52.8 %) followed by 14-16 years age (37.4 %) In study cases, menstrual complaints (67.7 %) were most common indication to visit OPD, followed by complaints like irregular cycles (48.5 %), pain in abdomen (29.8 %), abnormal vaginal discharge (13.9 %), acne and hirsutism (13.6 %) and obesity (11.4 %). Other less common complaints were delayed puberty (4.5 %), Bartholin cyst/abscess (3.3 %), breast diseases (2.8 %), mass per abdomen (0.8 %) and urogenital malformations (0.8 %). On basis of history and relevant investigations, menstrual cycle related gynaecological problems such as dysmenorrhea (24.7 %), oligomenorrhoea (19.7 %), menorrhagia (16.9 %), metrorrhagia (14.9 %) and hypomenorrhea (11.4 %) were noted. Amenorrhea was noted in 9.8 % cases, 1.5 % had primary amenorrhea while 8.3 % cases had secondary amenorrhea. Other problems were anaemia (28.8 %), urinary tract infection (19.7 %), PID (12.4 %), teenage pregnancy (2.3 %) and ovarian cyst (1.0 %). Conclusion: In present study menstrual cycle related gynaecological problems (dysmenorrhea, oligomenorrhoea, menorrhagia, hypomenorrhea, amenorrhea), anemia, urinary tract infection and PID were common in adolescent girls attending gynaecology OPD.

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Aim: To assess the association of vitamin D status in preeclamptic and normal healthy pregnant women. Materials and Methods: Prospective case control study included 50 women with preeclampsia and 50 normotensive pregnant women. Serum vitamin D estimation was done. Correlation between vitamin D deficiency and preeclampsia was analysed statistically. Results: Prevalence of vitamin D deficiency was comparable in both groups. Mean vitamin D level (19.7±2.79 ng/ml) was statistically low in preeclampsia group while in that of control was 24.3±1.89 ng/ml. Severity of vitamin D deficiency correlated with the severity of preeclampsia. Age, parity and BMI were similar in both the groups. No statistically significant difference seen regarding mode of delivery in both the groups. Conclusion: Vitamin D deficiency is significantly associated with preeclampsia. Further studies are needed to document the role of vitamin D supplementation in prevention of preeclampsia.

Background: Placenta accreta spectrum is a pathologic condition of placentation in which the villous tissue adheres or invades the uterine wall. Present study was aimed to study cases of abnormal placentation in the form of placenta accreta spectrum and the maternal and perinatal outcomes associated with it in our hospital. Material and Methods: Present study was single-center, prospective, observational study, pregnant female, gestational age>32weeks, with morbidly adherent placenta diagnosed antenatally by USG/ DOPPLER/ MRI or per operatively (on table). Maternal & Perinatal, outcomes & parameters were studied. Results: Among 58 patients' majority were (43.1%) of the age group of 30 to 34 years, were third gravida (41.4%), 33 (56.9%) delivered before 37 weeks of gestation. 56 (96.6%) patients had at least one LSCS in past pregnancies, 22 (37.9%) had prior curettage, 20 (34.5%) had prior LSCS and curettage, 49 (84.5%) had associated placenta previa. 31 out of 58 patients (53.3%) were diagnosed with morbidly adherent placenta antenatally on ultrasound doppler or MRI and 27 patients (46.6%) were intraoperatively (on table) diagnosed. 33 (56.9%) were diagnosed with placenta percreta, 16 (27.6%) had placenta increta and 9 (15.2%) were diagnosed with placenta accreta. 48 (82.8%) patients had hysterectomy as the rst line of treatment. 47 patients (81%) were shifted to ICU, 23 patients (39.7%) had bladder injuries due to placenta percreta invading the bladder, 30 patients (51.7%) had haemorrhagic shock, sepsis was seen in 3 (5.2%) patients, 2 patients (3.4%) landed in DIC and there were 3 (5.2%) mortalities. 33 (56.8%) neonates had APGAR score at 5 mins of < 7, 58.6% were born preterm, 55.1% required NICU admissions, and 13.7% died in neonatal period. Conclusion: Morbidly adherent placenta is one of the most devastating complications in pregnancy, associated with signicant and increased maternal and perinatal mortality and morbidity.