Background: Continuing comprehensive assessment of population health gap is essential for effective health planning. This paper assessed changes in the magnitude and pattern of disease burden in Thailand between 1999 and 2004. It further drew lessons learned from applying the global burden of disease (GBD) methods to the Thai context for other developing country settings.Methods: Multiple sources of mortality and morbidity data for both years were assessed and used to estimate Disability-Adjusted Life Years (DALYs) loss for 110 specific diseases and conditions relevant to the country's health problems. Causes of death from national vital registration were adjusted for misclassification from a verbal autopsy study.

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Different studies on variations of cause-specific mortality provide different policy implications and suggestions. Some findings mirror existing health care and services. Costantini and others (2000) concluded that differences in proportions of cancer patients dying at home across 13 provinces in Italy could not be explained by the known determinants, suggesting inappropriate hospital admission in the terminal phase of cancer. A study on geographical variations in breast cancer mortality in older American women by Goodwin and others (2002) suggested ways to improve the quality of breast cancer care. Some studies suggest further research in specific areas.