Nerium indicum is evergreen plant belonging to the Apocynaceae Family. The plant species collected in state of Madhya Pradesh, India. The flowers of Nerium indicum were collected locally, shade dried and extracted with petroleum ether and methanol by using Soxhlet apparatus. The preliminary phytochemical screening was carried out for the presence of alkaloids, flavonoids, carbohydrate glycosides, tannins, terpeniods, phenol and absence of steroids and saponins for methanolic extracts of Nerium indicum (flowers). The physical evaluation was carried out for the determination of methanol-soluble extractive value, watersoluble extractive value, Hexane-soluble extractive value; ash value includes total ash, acid insoluble ash and water-soluble ash, and moisture content for flowers of Nerium indicum.

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