Introduction: Labour induction is one of the most common procedure in obstetrics .Oxytocin is one of the time tested drug , but certain disadvantages associated with oxytocin can be countered by using misoprostol as labour inducing agent. Objectives: 1. To know the efficacy of oral Misoprostol solution in inducing labour 2. To calculate the induction delivery interval 3.To know the maternal and fetal outcome in the study population. Methodology: A prospective observational hospital based study involving 200 term pregnant patients getting admitted to the labour ward. All of them were induced with oral misoprostol in solution form at a static dose regimen, second hourly (20 ug) for a total of five doses. Labour monitored as per the labour room protocol, reassessed after five doses or earlier as per clinical progress. Results: 200 patients were included, the efficacy of its use was excellent, mean number of doses required was 5, with the average induction delivery interval of 13.65 hrs, with 77.5% of vaginal delivery rate and 22.5% of caesarean rate, 30% needed oxytocin augmentation and 6.5% of the babies had meconium staining of liquor, of them 23.08% showed signs of meconium aspiration syndrome and one perinatal death was noted in the study. Conclusion:Oral misoprostol solution in static dosage is a simple, safe and effective method for induction of labour at term.

Background: Covid-19 presents with plethora of symptoms & signs, whereas pregnant people might be at increased risk for severe illness from COVID-19 compared to non-pregnant people probably due to changes in anatomy, endocrine, and immune factors during pregnancy. Additionally, there may be an increased risk of adverse pregnancy outcomes, such as preterm birth, intrauterine fetal demise. Case report: A 35yr old G3P2L2 with 33 weeks 1 day of gestation with prev 2 lscs with COVID-19 positive with severe respiratory distress admitted to ICU for ventilator support. She required an emergency caesarean section in view of deteriorating medical condition. 14 days postnatally, both mother & baby were discharged with no complications. Conclusion: Covid-19 in pregnancy pose a imperative aspect in its management as we do not have set guidelines on management of pregnant women & her baby in critical care setup during this pandemic. Decision making for delivery should highlight the balance of risk & benefit for maternal status & fetal status.

Cervical cancer is the leading genital malignancy in India, there is a dire need to schedule screening programs on a regular basis. Objectives: 1) To compare the efficacy of visual, cytological and HPV DNA testing as primary cancer screening methods for the detection cervical intraepithelial neoplasia and cancer.2) Colposcopic evaluation and directed biopsy for positive cases. Methodology: Prospective observational study including 100 married women in the age group 35-50 years for opportunistic screening were enrolled and they underwent a visual inspection of the cervix followed by cytology (PAP smear) and HPV DNA testing at the same visit. Results: Visual inspection and Pap smear as screening methods had good specificity but low sensitivity values, as compared to HPV. Conclusion: HPV testing serves as a more reliable and cost effective screening method, can be considered as a gold standard one step screening method for preinvasive lesions of the cervix.