The shear walls are essential seismic elements to increase buildings bearing capacity against earthquakes. In mid- and high-rise buildings, shear walls are subjected to predominant bending deformation under earthquakes, and the responses in upper floors increase. In order to utilize the shear walls appropriately, previous studies proposed to install shear walls until a certain building level, referred to as the curtailed wall. However, the upper frame structure without shear walls suffered significant deformation during earthquakes compared to the lower stories. Therefore, the objective of this study is to present structural configuration for buildings with curtailed shear walls by installing buckling-restrained braces (BRBs) in the upper frame to reduce its deformation under earthquakes. Firstly, the analysis accuracy was verified by simulating the experimental results of four sets of scaled frames with curtailed walls tested on a shaking table. Then, ten- and twenty-story plane frames with the different heights of curtailed walls were created, and their nonlinear responses to earthquake ground motions were evaluated. The genetic algorithm was applied to establish the optimum BRB locations to satisfy the design criteria. It was proved that using BRBs at specific locations in upper frames can significantly improve the seismic response of buildings with curtailed walls.