Irritable bowel syndrome (IBS) is the most common functional gastrointestinal disorder in western countries. Previous studies on IBS, mostly based on faecal samples, suggest alterations in the intestinal microbiota. However, no consensus has been reached regarding the association between specific bacteria and IBS. We explore the alterations of intestinal bacterial communities in IBS using massive sequencing of amplified 16S rRNA genes. Mucosal biopsies of the ascending and descending colon and faeces from 16 IBS patients and 9 healthy controls were analysed. Strong inter-individual variation was observed in the composition of the bacterial communities in both patients and controls. These communities showed less diversity in IBS cases. There were larger differences in the microbiota composition between biopsies and faeces than between patients and controls. We found a few over-represented and under-represented taxa in IBS cases with respect to controls. The detected alterations varied by site, with no changes being consistent across sample types.

Incontinence-associated dermatitis: a cohort study in critically ill patients ABSTRACTObjectives: Estimate incidence, determine risk factors and propose a prediction model for the development of incontinence-associated dermatitis critically ill adult patients. Method: Concurrent cohort study with 157 critically ill patients. Data collection was daily performed between February and July 2015, at a public teaching hospital of Belo Horizonte, Minas Gerais. Data was entered in a database and subjected to descriptive, survival and multivariate analysis. Results: An overall incidence of 20.4% was obtained. Nineteen (19) risk factors significantly associated with the disorder were found. The variables identified in the risk prediction model were male, trauma, use of hypnotics/sedatives, lactulose, nutritional support, loose stools and complaints of burning. Conclusion:The results showed that dermatitis is a common clinical finding in critically ill adult patients and requires special attention from the nursing staff.

This is a descriptive study with the aim of examining the nursing diagnoses labels and actions prescribed by nurses in the clinical records of patients hospitalized in an Adult Intensive Care Unit. A sample of 44 clinical records was obtained and a total of 1087 nursing diagnoses and 2260 nursing actions were identified. After exclusion of repetitions 28 different nursing diagnoses labels and 124 different nursing actions were found. Twenty-five nursing diagnoses labels were related to human psychobiological needs and three to psychosocial needs. All the nursing actions were mapped to the physiological needs and also to interventions of the Nursing Interventions Classification-NIC. Concordance of 100% was obtained between the experts in the validation process of the mapping performed, both for the nursing diagnoses labels and actions. Similar studies should be conducted for the identification and development of nursing diagnoses and actions.

Objective: to assess the predictive validity of the Manchester Triage System implemented in a municipal hospital in Belo Horizonte, MG, Brazil. Method: cohort prospective and analytical study. The sample of 300 patients was stratified by color groups. The outcome measured was the scores, obtained by patients in each classification group in the Therapeutic Intervention Scoring System -28, 24 hours after admission to the emergency department. Results: A total of 172 (57%) patients were men and the average age of all patients was 57.3 years old. The median score concerning the severity of their conditions was 6.5 points in the yellow group, 11.5 in the orange group, and 22 points in the red group. Statistically significant differences were found among the three groups (p<0.001). Conclusion: the data confirm that the conditions of patients within the color groups progressed at different levels of severity. Validez predictiva del Protocolo de Clasificación de Riesgo de Manchester: evaluación de la evolución de los pacientes admitidos en un pronto atendimientoObjetivo: evaluar la validez predictiva del protocolo de clasificación de riesgo de Manchester implantado en un hospital municipal de Belo Horizonte, Minas Gerais. Método: estudio de cohorte prospectivo y analítico. La muestra estratificada por colores de la clasificación fue de 300 pacientes. El final evaluado fue la puntuación por el Therapeutic Intervention Scoring System -28, lograda por los pacientes en cada grupo de clasificación después de 24 horas de la admisión en el servicio de urgencia. Resultados: entre los pacientes, 172 eran hombres (57%); la media de edad de los pacientes evaluados fue de 57,3 años. La mediana de puntuación del índice de gravedad en el grupo amarillo fue 6,5 puntos; en el grupo naranja, 11,5 puntos y, en el grupo rojo, 22 puntos, habiendo diferencia estadística significante entre los tres grupos (p<0,001). Conclusión: los datos refuerzan que los pacientes evolucionan con niveles de gravedad diferentes entre los grupos de colores de clasificación.