The reality of a rapidly changing healthcare arena forces nursing professionals to continually keep pace with advancements in nursing practice. Similarly, those responsible for educating future nurses must continue to keep abreast of changes in healthcare and nursing practice. Maintaining an up-to-date curriculum prepares nurses to adequately meet current and future challenges to the profession. This article outlines the processes undertaken by one comprehensive university in the United States to revise its graduate curriculum to prepare students for graduate-level nursing practice and to function as leaders within the healthcare arena.