Objective To determine the prevalence of depression and burnout among residents in paediatrics and to establish if a relation exists between these disorders and medication errors. Design Prospective cohort study. Setting Three urban freestanding children's hospitals in the United States. Participants 123 residents in three paediatric residency programmes. Main outcome measures Prevalence of depression using the Harvard national depression screening day scale, burnout using the Maslach burnout inventory, and rate of medication errors per resident month. Results 24 (20%) of the participating residents met the criteria for depression and 92 (74%) met the criteria for burnout. Active surveillance yielded 45 errors made by participants. Depressed residents made 6.2 times as many medication errors per resident month as residents who were not depressed: 1.55 (95% confidence interval 0.57 to 4.22) compared with 0.25 (0.14 to 0.46, P<0.001). Burnt out residents and non-burnt out residents made similar rates of errors per resident month: 0.45 (0.20 to 0.98) compared with 0.53 (0.21 to 1.33, P=0.2). Conclusions Depression and burnout are major problems among residents in paediatrics. Depressed residents made significantly more medical errors than their nondepressed peers; however, burnout did not seem to correlate with an increased rate of medical errors.

In a study of 10 North Carolina hospitals, we found that harms remain common, with little evidence of widespread improvement. Further efforts are needed to translate effective safety interventions into routine practice and to monitor health care safety over time. (Funded by the Rx Foundation.).

Adverse event rates in the NICU setting are substantially higher than previously described. Many adverse events resulted in permanent harm and the majority were classified as preventable. Only 8% were identified using traditional voluntary reporting methods. Our NICU-focused trigger tool appears efficient and effective at identifying adverse events.

Institute of Medicine concluded that between 44 000 and 98 000 deaths per year occur in hospitals in the United States as a result of errors. Since publication, these data have captured the attention of the nation, 2,3 resulting in aggressive calls for further research, 4,5 regulatory interventions, [6][7][8] third-party payer involvement, 9,10 and health care organization initiatives to improve this situation. One such initiative, promoted by the Institute for Healthcare Improvement known as the 100 000 Lives Campaign, recommended 6 strategies to decrease the number of preventable inpatient deaths in the United States by 100 000 during the period between December 2004 and June 2006. 11 One of these 6 recommended strategies was the implementation of a rapid response team (RRT).An RRT, also known as a medical response team or medical emergency team, is a multidisciplinary team most frequently consisting of intensive care For editorial comment see p 2311.