Electronic cigarettes (E-Cigs) have been advertised as a safer alternative to smoking. However, E-Cigs use, like smoking, delivers ultra-small aerosol particles, which may be associated with cardiovascular disease. This study aimed to look into the association between E-Cigs use and cardiovascular disease outcomes. The study involved self-reported data from 16,855 participants from the
Introduction:
In 2016, 3.2% of US adults and 11.3% of high school students reported using electronic cigarettes (e-cigarettes) in the preceding 30 days. Its use among young people increased by 900% between 2011 and 2015. Stroke occurs in 795,000 people and causes 133,000 deaths annually in the US. The association between e-cigarette use and stroke is unknown. The purpose of this study was to determine the association between e-cigarette use and stroke.
Methods:
The study is an analysis of the 2016 Behavioral Risk Factor Surveillance System (BRFSS) an annual chronic disease and behavioral risk factor survey conducted by the CDC. The sample included 66,795 respondents that reported ever regularly using e-cigarettes. The control group was the 343,856 respondents that reported never using e-cigarettes. Odds ratios were calculated using logistic regression analysis. Among the covariates tested, age, sex, smoking status, diabetes, exercise and Body Mass Index (BMI) categories showed significant effects on the model and were adjusted for in the outcomes.
Results:
Overall 21% of BRFSS respondents reported ever using e-cigarettes, with 48.5% of them being female (P <0.0001). Compared with non-users, e-cigarette users had a lower mean age (44 vs 57 years [P <0.0001]), lower mean BMI (27.7 vs 28.1 [P <0.0001]) and a lower rate of diabetes (9.8% vs 12.1% [P <0.0001]). They however had higher rates of cigarette smoking (78.7% vs 37.4% [P <0.0001]). Compared with non-users, e-cigarette users had higher adjusted odds of stroke (OR 1.71 [1.64 - 1.8]), myocardial infarction (OR 1.59 [1.53 - 1.66]), angina or coronary heart disease (OR 1.4 [1.35 - 1.46]).
Conclusion:
E-cigarette use is associated with higher odds of stroke, myocardial infarction and angina/coronary heart disease.
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