Background-In a correlative functional/histopathologic study, we investigated the regional deformation characteristics of both chronic nontransmural and transmural infarctions before and after a dobutamine challenge. Methods and Results-After stenosing copper-coated stent implantation to produce circumflex artery endothelial proliferation, 18 pigs were followed up for 5 weeks. Posteuthanasia histology showed 10 to have a nontransmural and 8 a transmural infarction. Eight nonstented animals served as controls. Regional radial function was monitored by measuring ultrasound-derived peak systolic strain rates (SR SYS ) and systolic strains (⑀ SYS ) (1) before stent implantation and (2) at 5 weeks, at baseline (bs) and during an incremental dobutamine infusion. In controls, dobutamine induced a linear increase in SR SYS (dobutamine: bs, 4.8Ϯ0.4 s
Articles you may be interested inElectrical characteristics and reliability properties of metal-oxide-semiconductor field-effect transistors with La 2 O 3 gate dielectric J. Appl. Phys. 100, 074108 (2006); 10.1063/1.2356902 Model for the voltage and temperature dependence of the soft breakdown current in ultrathin gate oxides
The time dependence of the gate voltage VG(t) after soft breakdown of metal-oxide-semiconductor capacitors with a 2.4 nm SiO2 layer has been measured. It is found that the VG(t) fluctuation distributions are non-Gaussian, but can be described by a Lévy stable distribution. The long-range correlations in VG(t) are investigated within the detrended fluctuation analysis. The Hurst exponent is found to be H=0.25±0.04 independent of the value of the stress current density J. It is argued that these are universal features of soft breakdown and are due to trapping–detrapping of electrons in and away from the primary percolation path.
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