In trained men, and considering the limitations of the current design (e.g., inclusion of selected oxidative stress and antioxidant biomarkers measured in blood only), strenuous bouts of exercise do not result in a significant increase in blood oxidative stress during the 1-h postexercise period. These findings may be related to attenuation in reactive oxygen species production as an adaptation to chronic exercise training and/or a protective effect of the antioxidant system in response to acute strenuous exercise.
Background:1,3-dimethylamylamine is a commonly used ingredient within dietary supplements. Our prior work with this agent indicates a transient increase in blood pressure (systolic in particular) following oral ingestion of a single dosage, but no significant increase in resting blood pressure following chronic ingestion. Moreover, intervention studies involving both two and eight weeks of treatment with finished products containing 1,3-dimethylamylamine indicate minimal or no change in bloodborne markers of health. The present study sought to extend these findings by using a 10-week intervention trial to determine the change in selected markers of health in a sample of men.Methods:25 healthy men were randomly assigned to either a placebo (n = 13) or to a supplement containing 1,3-dimethylamylamine (n = 12) for a period of 10 weeks. Before and after the intervention, resting blood pressure and heart rate were measured, and blood samples were collected for determination of complete blood count, metabolic panel, and lipid panel.Results:No significant differences were noted between conditions for blood pressure (P > 0.05), although systolic blood pressure increased approximately 6 mmHg with the supplement (diastolic blood pressure decreased approximately 4 mmHg). A main effect for time was noted for heart rate (P = 0.016), with values decreasing from pre to post intervention. There were significant main effects for time for creatinine (increased from pre to post intervention; P = 0.043) and alkaline phosphatase (decreased from pre to post intervention; P = 0.009), with no condition differences noted (P > 0.05). There was a significant interaction noted for low density lipoprotein cholesterol (LDL-C) (P = 0.043), with values decreasing in the supplement group from pre to post intervention approximately 7 mg · dL−1 (P = 0.034). No other effects of significance were noted for bloodborne variables.Conclusion:These data indicate that a dietary supplement containing 1,3-dimethylamylamine does not result in a statistically significant increase in resting heart rate or blood pressure (although systolic blood pressure is increased ∼6 mmHg with supplement use). The supplement does not negatively impact bloodborne markers of health. Further study is needed involving a longer intervention period, a larger sample size, and additional measures of health and safety.
The current U.S. Navy Physical Readiness Test (PRT) measures aerobic fitness and muscular endurance via a 1 1/2 mile run and curl-up/push-up tests, respectively. Nine new modalities were recommended to either replace or supplement the current PRT. Personnel and civilians (N = 179) were recruited from a local Navy base and participated in all modalities (duplicate if possible) over 4 weeks following familiarization sessions. Subjects performed single-leg plank, single-leg wall squat, cadence push-ups, leg/hip dynamometer, standing long jump, and pro-agility test. Cardiovascular modalities were also performed via the 300-yard shuttle, 2-km row, and 5-km bike. Performance in the modalities was correlated to the subjects' existing PRT scores as well as within the new modalities. Although most modalities could not be concretely recommended, the plank and wall squat were eliminated from consideration because of poor reliability scores. The strongest correlation existed between the standing long jump and pro-agility test for the entire sample. Correlation scores were also analyzed by gender. The cardiovascular modalities did not have strong enough scores to elicit a recommendation to replace the 1 1/2 mile run, but future considerations for similar testing would be to collect scores for the existing modalities in addition to the proposed modalities.
Recreational exercisers continue to take a greater interest in monitoring their personal fitness levels. One of the more notable measurements that are monitored and estimated by wrist-worn tracking devices is maximum aerobic capacity (VO2max), which is currently the accepted measure of cardiorespiratory fitness. Traditional methods of obtaining VO2max present expensive barriers, whereas new wearable technology, such as of the Garmin Fenix 5x (GF5) provides a more cost-effective alternative. PURPOSE: To determine the validity of the GF5 VO2max estimation capabilities against the ParvoMedics TrueOne 2400 (PMT) metabolic measurement system in recreational runners. METHODS: Twenty-five recreational runners (17 male and 8 female) ages 18-55 participated in this study. Participants underwent two testing sessions: one consisting of the Bruce Protocol utilizing the PMT, while the other test incorporated the GF5 using the Garmin outdoor protocol. Both testing sessions were conducted within a few days of each other, with a minimum of 24 hours rest between sessions. RESULTS: The mean VO2max values for the PMT trial (49.1 ± 8.4 mL/kg/min) and estimation for the GF5 trial (47 ± 6.0 mL/kg/min) were found to be significantly different (t = 2.21, p = 0.037). CONCLUSION: The average difference between the GF5 estimation and the PMT was 2.16 ml/kg/min. Therefore, the watch is not as accurate compared to a PMT for obtaining VO2max. However, although not statically significant, the proximity of scores to the PMT shows that the GF5 can be an option for a person seeking an affordable and easily available method of determining VO2max.
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